Effect of Acori graminei Rhizoma on Contractile Dysfunction of Ischemic and Reperfused Rat Heart(Pharmacognosy)

スポンサーリンク

概要

• 論文の詳細を見る

• Acori graminei Rhizoma is one of the best-known traditional herbal medicines frequently used for the treatment of cardiovascular symptoms in Asian countries. The anti-ischemic effect of Acori graminei Rhizoma on ischemia-induced isolated rat heart was investigated through analysis of changes in perfusion pressure, aortic flow, coronary flow, and cardiac output. The subjects in this study were divided into two groups, an ischemia-induced group without any treatment (I), and an ischemia-induced group with Acori graminei Rhizoma treatment (I+AGR). There were no significant differences in perfusion pressure, aortic flow, coronary flow, or cardiac output between the two groups before ischemia was induced. The supply of oxygen and buffer was stopped for 10 min to induce ischemia in isolated rat hearts, and Acori graminei Rhizoma was administered while inducing ischemia. The data showed that Acori graminei Rhizoma treatment significantly prevented decreases in perfusion pressure, aortic flow, coronary flow, and cardiac output under an ischemic condition. In addition, hemodynamics (except heart rate) of the AGR-treated group was significantly recovered 60 min after reperfusion compared to the control group, (systolic aortic pressure: 85.5% vs. 62.5%, aortic flow volume: 68.1% vs. 49.4%, coronary flow volume: 86.8% vs. 60.1%, and cardiac output: 73.1% vs. 54.1%, p<0.01). These results suggest that Acori graminei Rhizoma has distinct anti-ischemic effects.

• 社団法人日本薬学会の論文
• 2006-03-01

著者

• Bae Hyunsu

  Dep. Of Physiology Coll. Of Oriental Medicine Kyung Hee Univ.

• Hong Moochang

  Dep. Of Physiology Coll. Of Oriental Medicine Kyung Hee Univ.

• CHUNG Hwan-Suck

  Purimed R&D Institute, Kyung Hee University

• KANG Moonkyu

  Purimed R&D Institute, Kyung Hee University

• CHO Chongwoon

  Purimed R&D Institute, Kyung Hee University

• SHIN Minkyu

  Department of Physiology, College of Oriental Medicine, Kyung Hee University

• HONG Moochang

  Department of Physiology, College of Oriental Medicine, Kyung Hee University

• BAE Hyunsu

  Purimed R&D Institute, Kyung Hee University

• KIM Jong-Hoon

  Research Laboratory for the Study of Ginseng Signal Transduction and Department of Physiology, Colle

• YOON You-Sik

  Korea Institute of Oriental Medicine

• LEE Youngseop

  Department of Physiology, College of Oriental Medicine, Kyung-Hee University

• Kim Jong-hoon

  Research Laboratory For The Study Of Ginseng Signal Transduction And Department Of Physiology Colleg

• Chung Hwan-suck

  Department Of Pharmacology College Of Oriental Medicine Kyung Hee University:department Of Oriental

• Chung Hwan-suck

  College Of Pharmacy Wonkwang University

• Chung Hwan-suck

  College Of Pharmacy Vestibulocochlear Research Center Of Wonkwang University

• Shin Minkyu

  Dep. Of Physiology Coll. Of Oriental Medicine Kyung Hee Univ.

• Kang M

  Purimed R&d Institute Kyung Hee University

• Lee Youngseop

  Department Of Physiology College Of Oriental Medicine Kyung-hee University

• Cho Chongwoon

  Purimed R&d Institute Kyung Hee University

• Kang Moonkyu

  Purimed R&d Institute Kyung Hee University

• Chung Hwan-suck

  Dep. Of Pathology Coll. Of Oriental Medicine Kyung Hee Univ.

• BAE Hyunsu

  Purimed R&D Institute, Kyung Hee University:Department of Physiology, College of Oriental Medicine, Kyung Hee University

• Chung Hwan-Suck

  Purimed R&D Institute, Kyung Hee University

関連論文

• The Genome-Wide Expression Profile of Nelumbinis semen on Lipopolysaccharide-Stimulated BV-2 Microglial Cells
• Regulatory Effect of Dosiinpartner on High-Fat Diet-Induced Obesity in C57BL/6J Mice(Pharmacology)
• Induction of Nitric Oxide Synthase by Oldenlandia diffusa in Mouse Peritoneal Macrophages
• Molecular Authentication of Panax ginseng Species by RAPD Analysis and PCR-RFLP
• The Immune-Enhancing Effect of the Herbal Combination Bouum-Myunyuk-Dan(Pharmacology)
• Inhibition of Nitric Oxide and Tumor Necrosis Factor-Alpha by Moutan Cortex in Activated Mouse Peritoneal Macrophages(Pharmacognosy)
• Effects of Yukmijihwang-tang Derivatives (YMJd) on Ibotenic Acid-Induced Amnesia in the Rat(Pharmacognosy)
• Effect of Acori graminei Rhizoma on Contractile Dysfunction of Ischemic and Reperfused Rat Heart(Pharmacognosy)
• Inhibition of Production of Reactive Oxygen Species and Gene Expression Profile by Treatment of Ethanol Extract of Moutan Cortex Radicis in Oxidative Stressed PC12 Cells(Pharmacognosy)
• Effects of Yukmijihwang-tang Derivatives (YMJd), a Memory Enhancing Herbal Extract, on the Gene-Expression Profile in the Rat Hippocampus(Pharmacognosy)
• Anti-obesity Effect of PM-F2-OB, an Anti-obesity Herbal Formulation, on Rats Fed a High-Fat Diet(Pharmacognosy)
• So-Cheong-Ryong-Tang, Tradititional Korean Medicine, Suppresses Th2 Lineage Development (Pharmacognosy)
• Chung-Yeul-Gue-Soup-Sa-Gan-Tang, Traditional Korean Medicine, Enhances CD4^+ T Cell Activities and Modulates Th1/Th2 Lineage Development
• Immunomodulatory Effect of Astragali Radix Extract on Murine Th1/Th2 Cell Lineage Development(Pharmacology)
• Inhibitory Effect of High Molecular Weight Water-Soluble Chitosan on Hypoxia-Induced Inflammatory Cytokine Production

もっと見る 閉じる

スポンサーリンク