Iridoids from Neopicrorhiza scrophulariiflora and Their Hepatoprotective Activities in Vitro
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概要
- 論文の詳細を見る
Four new non-glycosidic iridoids, piscrocins D (1), E (2), F (6), and G (7), as well as two new iridoid glycosides, piscrosides A (8) and B (9), were isolated from the roots of Neopicrorhiza scrophulariiflora (Scrophulari-aceae), together with seven known iridoids. The structures of the isolated compounds were established by means of 1D and 2D NMR spectroscopy and chemical methods. The hepatoprotective activities of these compounds were evaluated by measuring their effects on CCl_4-induced hepatocytes damage in vitro, and the structure-activity relationships were also discussed.
- 社団法人日本薬学会の論文
- 2006-08-01
著者
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Zhang Lu-yong
National Drug Screening Lab. China Pharmceutical Univ.
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LI Ping
Key Laboratory of Modern Chinese Medicines (China Pharmaceutical University), Ministry of Education
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Wang Hao
Department of Natural Medicinal Chemistry, China Pharmaceutical University
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Li Ping
Key Laboratory Of Modern Chinese Medicines Ministry Of Education China Pharmaceutical University:dep
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Li Ping
Key Laboratory Of Modern Chinese Medicines (china Pharmaceutical University) Ministry Of Education:d
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Wang H
Peking Univ. Beijing Chn
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Wang Hao
中華人民共和国
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Wang Hao
State Key Lab Of Advanced Technology For Materials Synthesis And Processing Wuhan University Of Tech
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Wang Hao
Department Of Cardiology First Teaching Hospital Xi'an Medical University
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Ye Wen-cai
Guangdong Province Key Lab. Of Pharmacodynamic Constituents Of Tcm And New Drugs Res. Jinan Univ.
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Ye Wen-Cai
Department of Phytochemistry, China Pharmaceutical University
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WU Fei-Hua
Department of Pharmacology for Chinese Materia Medica, China Pharmaceutical University
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XIONG Fei
Department of Pharmacology for Chinese Materia Medica, China Pharmaceutical University
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WU Jia-Jun
Department of Natural Medicinal Chemistry, China Pharmaceutical University
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ZHAO Shou-Xun
Department of Natural Medicinal Chemistry, China Pharmaceutical University
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Wu Jia-jun
Department Of Natural Medicinal Chemistry China Pharmaceutical University
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Wu Fei-hua
Department Of Pharmacology For Chinese Materia Medica China Pharmaceutical University
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Ye W‐c
Guangdong Province Key Lab. Of Pharmacodynamic Constituents Of Tcm And New Drugs Res. Jinan Univ.
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Wang Hao
Dep. Of Natural Medicinal Chemistry China Pharmaceutical Univ.
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Ye Wen-cai
Department Of Phytochemistry China Pharmaceutical University
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Ye Wen-cai
Department Of Natural Medicinal Chemistry China Pharmaceutical University:institute Of Traditional C
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Zhao S‐x
Department Of Natural Medicinal Chemistry China Pharmaceutical University
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Xiong Fei
Department Of Pharmacology For Chinese Materia Medica China Pharmaceutical University
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Wang H
Department Of Natural Medicinal Chemistry China Pharmaceutical University
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Li Ping
Key Lab. Of Heavy Ion Radiation Biology And Medicine Of Chinese Acad. Of Sciences
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