New Triterpenoids Isolated from the Root Bark of Ulmus pumila L.

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概要

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• Three new triterpenoids, 1-3, were isolated from the dried root bark of Ulmus pumila. Along with the three new compounds, six known triterpenoids, epifriedelanol (4), friedelin (5), oleanolic acid (6), maslinic acid (7), camaldulenic acid (8), and arjunolic acid (9) were also isolated. The structures of new compounds were established as ulmudiol (bauer-7-ene-1α,3β-diol, 1), dehydroulmudiol [bauer-7,9(11)-diene-1α,3β-diol, 2], and ulmuestone [3α-hydroxy-11α-(4'-hydroxy-3'-methoxy)benzoyloxybauer-1-one, 3], on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. In addition, the cytotoxic activities of these compounds are also reported.

• 公益社団法人日本薬学会の論文
• 2006-06-01

著者

• Wang Dong

  中華人民共和国

• WANG Dong

  Department of Radiological and Medical Laboratory Sciences

• Wang D

  Kyushu Univ. Fukuoka Jpn

• Wang Dong

  Department Of Pharmacognosy School Of Traditional Chinese Materia Medica Shenyang Pharmaceutical Uni

• Zhang Chun-ling

  China-japan Research Institute Of Medical And Pharmaceutical Sciences Shenyang Pharmaceutical Univer

• XIA Mingyu

  China-Japan Research Institute of Medical and Pharmaceutical Sciences, Shenyang Pharmaceutical Unive

• CUI Zheng

  Department of Pharmacognosy, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical U

• Xia Mingyu

  China-japan Research Institute Of Medical And Pharmaceutical Sciences Shenyang Pharmaceutical Univer

• Wang Dong

  Department Of Electronics And Mechanical Engineering Faculty Of Engineering Chiba University

• Cui Zheng

  Department Of Pathology Wake Forest University School Of Medicine

• Wang Dong

  Department Of Anatomy Histology And Embryology Chinese Academy Of Medical Sciences Peking Union Medi

• Xia Mingyu

  China-Japan Research Institute of Medical and Pharmaceutical Sciences, Shenyang Pharmaceutical University

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