Impact of Atrial Septal Defect Closure on Right Ventricular Performance
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概要
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Background Atrial septal defect (ASD) closure is one of the most representative cardiac operations, but there have been few assessments of right ventricular (RV) performance during the perioperative period. Methods and Results Using transesophageal echocardiography with automated border detection system, the RV pressure-area (P-A) loops were measured in 6 patients immediately before and after an ASD closure. Multiple RV P-A loops obtained by the inferior vena cava occlusion technique were used to evaluate end-systolic maximal elastance (E_<es>), preload recruitable stroke work (MEW), external work (EW) and the systolic P-A area (PAA). E_<es> and MEW are indices of contractility, and PAA represents the total mechanical energy. RV E_<es> and MEW did not change after the operation (from 3.36±2.20 to 3.70±2.04mmHg/cm^2, p=0.4; and from 10.3±5.0 to 10.5±4.5mmHg, p=0.8, respectively), whereas EW and PAA were significantly reduced (from 121.4±77.4 to 48.7±26.6mmHg/cm^2, p<0.05; and from 274.8±212.8 to 92.7±52.8mmHg/cm^2, p<0.05, respectively). ASD closure reduced the EW and total mechanical energy of the right ventricle without influencing contractility. Conclusions These results indicate that ASD closure preserved RV function and reduced RV myocardial oxygen consumption. Assessment of the RV P-A relationship in the operating room demonstrates the beneficial effects of ASD closure on RV performance.
- 社団法人日本循環器学会の論文
- 2006-06-20
著者
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Tominaga Ryuji
Department of Cardiovascular Surgery, Graduate School of Medical Sciences, Kyushu University
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Tominaga Ryuji
Department Of Cardiovascular Surgery Faculty Of Medicine Kyushu University
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Tominaga Ryuji
九州大学 医学部循環器外科学分野
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MORITA SHIGEKI
Department of Cardiovascular Surgery, Faculty of Medicine, Kyushu University
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MASUDA MUNETAKA
Department of Cardiovascular Surgery, Faculty of Medicine, Kyushu University
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TANOUE Yoshihisa
Department of Cardiovascular Surgery, Kyushu Kosei-Nenkin Hospital
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Tomita Yukihiro
Department Of Cardiovascular Surgery Faculty Of Medicine Kyushu University
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Tomita Yukihiro
Division Of Cardiovascular Surgery Graduate School Of Medical Sciences Kyushu University
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OCHIAI Yoshie
Department of Cardiovascular Surgery, Kyushu Koseinenkin Hospital
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Tanoue Yoshihisa
Department Of Cardiovascular Surgery Faculty Of Medicine Kyushu University
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Ochiai Yoshie
Department Of Cardiovascular Surgery Kyushu University
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Ochiai Yoshie
Department Of Biomedical Engineering Lerner Research Institute
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Tominaga Ryuji
Department Of Cardiovascular Surgery Kyushu University Hospital
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Morita Shigeki
Department Of Cardiovascular Surgery Kyushu University Hospital
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Morita Shigeki
Department Of Cardiovascular Surgery And Cardiovascular Clinic
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Tominaga Ryuji
Department Of Cadiovasucular Surgery Kyushu University Faculty Of Medicine
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Masuda Munetaka
Department Of Cardiovascular Surgery Kyushu University Hospital
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Tominaga Ryuji
Department Of Cardiovascular Surgery Kyushu University School Of Medicine
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Tominaga Ryuji
Department Of Cardiovascular Surgery Kyushu University
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Tomita Yukihiro
Department Of Cardiovascular Surgery Kyushu University
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Tomita Yukihiro
Department Of Cardiovascular Surgery Kyushu University Graduate School Of Medical Sciences
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Morita Shigeki
Department Of Cardiovascular Surgery Kyushu University Graduate School Of Medical Sciences
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