Low Serum Albumin Level is Risk Factor for Patients with Percutaneous Endoscopic Gastrostomy

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概要

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• Objective In Japan, percutaneous endoscopic gastrostomy (PEG) has been used mainly in patients with stroke and dementia, who undertake oral ingestion voluntarily. We have used PEG for patients with various diseases in Saga Medical School Hospital, including postoperative recovery, malignant disease, and neurodegenerative diseases. This study evaluated prognostic factors in these patients regarding long-term survival. Methods We analyzed retrospectively all patients who received PEG at our hospital. During the period of 1998-2007, 84 patients (32 females, 52 males; mean age, 60.3 years, range 20-89 years) were followed for more than 1 year. We analyzed sex, age, total lymphocyte count, serum albumin level, presence of malignant diseases, cerebrovascular diseases, neurodegenerative disorders, poor general condition after surgical procedures, dementia before PEG, pneumonia before PEG, and complications of PEG placement. Results As for diseases, 23 patients had malignant diseases, 27 had cerebrovascular diseases, 19 had neurodegenerative disorders, 16 were in poor general condition after surgery for nonmalignant diseases, and 12 had dementia. Multivariate analysis indicated that risk factors for 1-year survival were low serum albumin level (≤2.9 g/dL), low lymphocyte count, and complications of malignant diseases. Low serum albumin level, low lymphocyte count, and malignant diseases were risk factors, and only the albumin level was a risk factor in those without malignant diseases. Conclusion Low serum albumin level was a risk factor for 1-year survival with PEG, which suggests that nutrient management before and during PEG placement should be monitored carefully.

著者

• Morita Shigeki

  Department Of Cardiovascular Surgery And Cardiovascular Clinic

• Tsuruoka Nanae

  Department Of Internal Medicine And Gastrointestinal Endoscopy Saga Medical School

• Hara Hideo

  Department Of Applied Physics Faculty Of Engineering Hiroshima University

• Node Koichi

  Department Of Cardiovascular & Renal Disease Medicine Saga University

• Miyazaki Kohji

  Department Of Gynecology Shimane Medical University

• Shimoda Ryo

  Department Of Gastroenterology Saga University

• Matsushima Toshio

  Department Of Neurosurgery Faculty Of Medicine Saga University

• Sakata Yasuhisa

  Department Of Internal Medicine And Gastrointestinal Endoscopy Saga Medical School

• Tominaga Naoyuki

  Department Of Internal Medicine And Gastrointestinal Endoscopy Saga Medical School

• Hayashi Shinichiro

  Department Of Applied Chemistry Keio University

• Hamasaki Yuhei

  Department Of Chemistry Department Of Infectious Medicine Kurume University School Of Medicine

• Iwakiri Ryuichi

  Department of Internal Medicine & Gastrointestinal Endoscopy, Saga Medical School

• Sakata Yasuhisa

  Departments of Internal Medicine, Saga Medical School

• Hara Hideo

  Departments of Internal Medicine, Saga Medical School

• Fujimoto Kazuma

  Departments of Internal Medicine, Saga Medical School

• Fujimoto Kazuma

  Department of Internal Medicine & Gastrointestinal Endoscopy, Saga Medical School

• Miyazaki Kohji

  Departments of Gastroenterology and General Surgery, Saga Medical School

• Tsuruoka Nanae

  Departments of Internal Medicine, Saga Medical School

• Hamasaki Yuhei

  Departments of Pediatrics, Saga Medical School

• Node Koichi

  Departments of Internal Medicine, Saga Medical School

• Hayashi Shinichiro

  Departments of Internal Medicine, Saga Medical School

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