The Effect of α_2-Agonist on IOP Rise Following Nd-YAG Laser Iridotomy
スポンサーリンク
概要
- 論文の詳細を見る
We have tested the effect of topical administration of 0.5% para-amino-clonidine (PAC), an adrenergic alpha 2 agonist, on intraocular pressure (IOP), protein and prostaglandin E_2 (PGE_2) concentration in aqueous humor following the laser application to the iris of albino rabbits. The irides received Q-switched Nd: YAG laser irradiation with the energy level ranging from 2 to 80 mJ with and without topical administration of PAC one-hour prior to and immediately following laser irradiation. The IOP was measured with an Alcon pneumotonometer prior to and hourly for 6-hours following laser application. Aqueous humor was withdrawn prior to and at 0.5, 1, 2, 4 hours following laser irradiation for determining protein (Lowry method) and PGE_2 (radioimmunoassay). Four to 6 rabbits were used for each experiment. The increase in IOP, protein and PGE_2 concentration following laser irradiation was demonstrated to be dependent on the amount of laser energy. PAC significantly suppressed the IOP rise and the elevation of protein content, while it failed to affect the increase in PGE_2.
- 東海大学の論文
著者
-
KAWAI Kenji
Department of Ophthalmology, Tokai University School of Medicine
-
Sugiyama Kazuhisa
Department Of Ophthalmology And Visual Sciences Kanazawa University Graduate School Of Medical Scien
-
Sugiyama Kazuhisa
Department Of Ophthalmology Kanazawa University School Of Medicine
-
KITAZAWA Yoshiaki
Department of Ophthalmology, Gifu University School of Medicine
-
Sugiyama Kazuhisa
Department Of Electrical And Electronic Engineering Musashi Institute Of Technology
-
KITAZAWA Yoshiaki
Akasaka Kitazawa Eye Clinic
-
Kitazawa Y
Akasaka Kitazawa Eye Clinic
-
Kitazawa Yoshiaki
Department Of Ophthalmology Gifu University School Of Medicine
-
Kawai Kenji
Department Of Civil And Environmental Engineering Hiroshima University
-
Kawai Kenji
Department of Aquaculture, Kochi University
-
SUGIYAMA Kazuhisa
Department of Ophthalmology, Kanazawa University School of Medicine
関連論文
- Suppression of Redox Activities of Rabbit Lens λ-Crystallin by Glutathionylation
- Epitaxial Growth of YBaCuO Films on Sapphire at 500℃ by Metalorganie Chemical Vapor Deposition
- Quantification of Retinal Nerve Fiber Defects in Glaucoma : Three-Dimensional Analysis by Heidelberg Retina Tomograph
- Prevalence of Normal-Tension Glaucoma and Primary Open-Angle Glaucoma in Patients With Collagen Diseases
- RELATIONSHIP OF NERVE FIBER LAYER DEFECTS AND PARAFOVEAL VISUAL FIELD DEFECTS IN GLAUCOMATOUS EYES
- EFFECTS OF BQ-123, AN ET_A RECEPTER-SELECTIVE ANTAGONIST, ON CHANGES OF INTRAOCULAR PRESSURE, BLOOD-AQUEOUS BARRIER AND AQUEOUS PROSTAGLANDIN CONCENTRATIONS CAUSED BY ENDOTHELIN-1 IN RABBIT
- THE EFFECTS OF ET_B RECEPTOR-SELECTIVE AGONIST ON IOP AND BLOOD-AQUEOUS BARRIER IN RABBIT EYES : ROLE OF CYCLOOXYGENASE PRODUCTS
- THE EFFECTS OF ENDOTHELIN-1 ON INTRAOCULAR PRESSURE AND PUPILLARY DIAMETER IN RABBITS
- Analysis of COL8A2 Gene Mutation in Japanese Patients with Fuchs' Endothelial Dystrophy and Posterior Polymorphous Dystrophy
- Silicon-Hydrogen Bonds in Silicon Native Oxides Formed during Wet Chemical Treatments
- Dacryoendoscopic Surgery and Tube Insertion in Patients with Common Canalicular Obstruction and Ductal Stenosis as a Frequent Complication
- Conjunctival Vasculature Patterns Influencing the Filtering Bleb Shape Following Trabeculectomy with Limbal-Based Conjunctival Flaps
- Takayasu Disease on the Centenary of Its Discovery
- A New System to Supply Carbon Dioxide Safely to Glaucoma Patients
- Effect of Diabetic Retinopathy on Redox State of Aqueous Humor and Serum Albumin in Patients with Senile Cataract
- First-Principles Evaluations of Machinability Dependency on Powder Material in Elastic Emission Machining
- Clinical Efficacy of Topical Nipradilol and Timolol on Visual Field Performance in Normal-Tension Glaucoma : A Multicenter, Randomized, Double-Masked Comparative Study
- Influence of Topical Betaxolol and Timolol on Visual Field in Japanese Open-angle Glaucoma Patients
- Efficacy and Safety of Latanoprost Eye Drops for Glaucoma Treatment : A 1-Year Study in Japan
- λ-Crystallin Related to Dehydroascorbate Reductase in the Rabbit Lens
- Neuroprotective Effects of R(-)-1-(benzo[b]thiophen-5-yl)-2-[2-(N, N-diethylamino)ethoxy]Ethanol Hydrochloride (T-588) Against Retinal Ganglion Cell Death Induced by Elevated Intraocular Pressure in Rat
- Cataract Development After Trabeculectomy With Mitomycin C : A 1-Year Study
- Effect of Trabeculectomy on Visual Field in Progressive Normal-Tension Glaucoma
- The Effect of α_2-Agonist on IOP Rise Following Nd-YAG Laser Iridotomy
- Effect of Mitomycin C Dissolved in Reversible Thermo-Setting Gel on the Outcome of Filtering Surgery in the Rabbit
- Visual Field Loss in Patients with Normal-Tension Glaucoma Under Topical Nipradilol or Timolol : Subgroup and Subfield Analyses of the Nipradilol-Timolol Study
- The Additive Effects on Intraocular Pressure of Combining Nipradilol 0.25% and Latanoprost 0.005% Ophthalmic Solutions : a Prospective, Randomized, Multicenter Study
- P4-16 A Case of Clear Cell Hepatocellular Carcinoma
- The Microendoscope for Ciliary Process Photocoagulation in Neovascular Glaucoma
- A SIMPLIFIED METHOD FOR EVALUATION OF THIXOTROPY OF CONCRETE
- Association Between Watershed Zone and Visual Field Defect in Normal Tension Glaucoma
- INFLUENCE OF SURFACE TEXTURE ON COLOR TRANSITION OF MORTAR
- SOILING OF CONCRETE SURFACES DUE TO MICROORGANISMS
- Temporal Modulation Transfer Function in Normal-Tension Glaucoma Patients
- The effect of electrical acupuncture-stimulation therapy using thermography and plasma endothelin (ET-1) levels in patients with progressive systemic sclerosis (PSS)
- Rotational, Vibratiornal and Translational Temperatures for Regular and Sequence Band Transitions in Waveguide C0_2 Laser
- Circadian variations of plasma levels of blood coagulation/fibrinolysis molecular markers in progressive systemic sclerosis (PSS)
- カンパチの類結節症進行における鰓の重要性
- Is there circadian variation of plasma endothelin (ET-1) in patients with systemic scleroderma (SSc)?
- The 23 Gauge Capsulorrhexis Forceps Having a Cystotome Function
- A case report of Intraocular Lens Luxation with the Capsular Bag after Vitrectomy
- Difference in Redox Status of Serum and Aqueous Humor in Senile Cataract Patients as Monitored via the Albumin Thiol-Redox State
- Aqueous Humor Dynamics Associated with the Phorbol Ester-Induced Decrease in Intraocular Pressure in the Rabbit
- Effect of Foreign Gas on ν_3-Mode Vibrational Temperature for Regular and Sequence Band Transitions in Waveguide CO_2 Lasers
- Effect of Foreign Gas on Gain and Rotational and Translational Temperatures for Regular and Sequence Band Transitions in Waveguide CO_2 Laser
- Reproducibility of Color Doppler Imaging for Orbital Arteries in Japanese Patients With Normal-Tension Glaucoma
- Clinical Evaluation of a New Formula of Timolol Maleate (WP-934 Ophthalmic Solution)
- Spontaneous Intraocular Pressure Reduction in Normal-Tension Glaucoma and Associated Clinical Factors
- A Method Using Sutures for Extraction of Subluxated Posterior Chamber Intraocular Lens and Transscleral Fixation : Spider Technique
- Comparison of 23 Gauge and 25 Gauge Anterior Capsulotomy Forceps
- Improved prediction of fellow-eye response in one-eye trials using multiple intraocular pressure measurements
- Amino Acid Sequence and Western Blot Analyses of Ascorbate Free Radical Reductase Purified from Rabbit Lens Soluble Fraction
- Intraocular Pressure After Descemet's Stripping and Non-Descemet's Stripping Automated Endothelial Keratoplasty
- Relationship between macular ganglion cell complex parameters and visual field parameters after tumor resection in chiasmal compression
- Dacryoendoscopic observation and incidence of canalicular obstruction/stenosis associated with S-1, an oral anticancer drug
- Clinical evaluation of non-Descemet stripping automated endothelial keratoplasty (nDSAEK)
- Comparison of efficacy of four prostaglandin analogues by bilateral treatment in healthy subjects
- Detection of visual field defects in pre-perimetric glaucoma using fundus-oriented small-target perimetry
- Descemet stripping automated endothelial keratoplasty for microcornea
- Inventory Data and Case Studies for Environmental Performance Evaluation of Concrete Structure Construction
- n-Type Nanocrystalline FeSi₂/intrinsic Si/p-Type Si Heterojunction Photodiodes Fabricated by Facing-Target Direct-Current Sputtering
- A Proposal of Concrete Structure Design Methods Considering Environmental Performance
- Relationship between optic disc ovality and horizontal disc tilt in normal young subjects
- Differentiation by imaging of superior segmental optic hypoplasia and normal-tension glaucoma with inferior visual field defects only