Tenascin takes part in the progress of pathological severity in cerebral falciparum infection
スポンサーリンク
概要
- 論文の詳細を見る
We examined plasma level of circulating form of tenascin (TC) in falciparum malaria patients, cerebral malaria and non cerebral malaria, and compared them to uninfected healthy persons. Plasma level of TC examined were significantly higher in malaria patients than in control persons (p<0.01). The results also show that among malaria patients, TC level was higher in the cerebral malaria patients compare to non cerebral malaria patients (p<0.10). Kinetics of TC level in plasma were related to kinetics of TNF-a level. Moreover, patients with higher level of TC showed higher level of parasitized erythrocytes binding ratio. Immunohistochemical study showed that TC was found in the cerebral microvessels of postmortem cerebral tissues from nine cerebral malaria cases. These results provide evidence that plasma level of TC correlates with the severity in cerebral malaria patients.
- 東海大学の論文
- 1998-08-29
著者
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KANBARA Hiroji
Department of Protozoology, Institute of Tropical Medicine, Nagasaki University
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KUSUHARA Yasuhiro
Department of Medical Zoology, Fujita Health University School of Health Sciences
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Kanbara H
Nagasaki Univ. Nagasaki Jpn
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Kanbara H
Department Of Protozoology Institute Of Tropical Medicine Nagasaki University
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Kanbara Hiroji
Department Of Protozoology Institute Of Tropical Medicine Nagasaki University
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Kusakabe Moriaki
Division Of Gastroenterology And Hepatology Department Of Internal Medicine (ohmori) School Of Medic
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Kanbara Hiroji
Department Of Protozoology Institute Of Tropical Medicine
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NAKAZAWA SHUSUKE
Department of Protozoology, Institute of Tropical Medicine, Nagasaki University
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AIKAWA MASAMICHI
Research Institute of Medical Sciences, Tokai University
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MAENO Yoshimasa
Department of Virology and Parasitology, Fujita Health University, School of Medicine
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NAGASE Keizo
Department of Virology and Parasitology, Fujita Health University, School of Medicine
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NAKABAYASHI Toshio
Department of Virology and Parasitology, Fujita Health University, School of Medicine
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Nagase Keizo
Department Of Virology And Parasitology Fujita Health University School Of Medicine
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Maeno Yoshimasa
Department Of Virology And Parasitology Fujita Health University School Of Medicine
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Nakabayashi Toshio
Department Of Virology And Parasitology Fujita Health University School Of Medicine
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Kusuhara Yasuhiro
Department Of Medical Technology Nagoya University School Of Health Sciences
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Kusuhara Yasuhiro
Department Of Virology And Parasitology Fujita Health University School Of Medicine
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Aikawa Masamichi
Research Institute Of Medical Sciences Tokai University
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Aikawa Masamichi
Research Institute Of Medical Science Tokai University Kanagawa Japan
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Kusakabe Moriaki
Division Of Experimental Animal Research The Institute Of Physical And Chemical Research
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Nakazawa Shusuke
Department Of Protozoology Institute Of Tropical Medicine Nagasaki University
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Nakazawa Shusuke
Department Of Protozoology Institute Of Tropical Medicine (nekken) And The Global Coe Program Nagasa
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NAKABAYASHI TOSHIO
Department of Agricultural Chemistry, Faculty of Agriculture, Shizuoka University
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