TRYPANOSOMA EVANSI: UNIQUE CONCAVITIES ON THE SURFACE MEMBRANE OF PARAROSANILINE-INDUCED AKINETOPLASTIC CLONES AS REVEALED BY SCANNING ELECTRON MICROSCOPY
スポンサーリンク
概要
- 論文の詳細を見る
Pararosaniline-induced akinetoplastic clones of Tmpanosoma evansi which lack DAPI-stainable kDNA network were characterized by scanning electron microscopy. Independent batches of akinetoplastic parasites from two passages in mice were observed to have similarities with parental kinetoplastic strain with respect to shape, form, and pleomorphism. The marked difference in surface topography was noted between the wildtype and the mutant as unique concavities on the cell surface of the latter. These concavities are variable in size, number and extent and may be inheritable. In addition, akinetoplastic cells were found to undergo active longitudinal binary fission and filopodia formation as reported by others. These observations suggest that the kDNA-deficient mutants of T. evansi have maintained their basic functions of cell division and infectivity and, therefore, the concavities on their surface are not detrimental to their existence.
- 日本熱帯医学会,Japanese Society of Tropical Medicineの論文
- 1995-03-15
著者
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Kanbara H
Nagasaki Univ. Nagasaki Jpn
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Kanbara Hiroji
藤田保健衛生大学 寄生虫
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Kanbara Hiroji
Department Of Protozoology Institute Of Tropical Medicine Nagasaki University
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Kanbara Hiroji
Department Of Protozoology Institute Of Tropical Medicine
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UEMURA Haruki
Department of Protozoology, Institute of Tropical Medicine (NEKKEN), Nagasaki University
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MARY ROSE
To whom all correspondence should be addressed
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ICHINOSE AKITOYO
Department of Protozoology, Institute of Tropical Medicine, Nagasaki University
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Uemura Haruki
Department Of Protozoology Institute Of Tropical Medicine (nekken) Nagasaki University
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Ichinose Akitoyo
Department Of Protozoology Institute Of Tropical Medicine Nagasaki University
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Silva-Tahat Mary
To whom all correspondence should be addressed
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