Pharmacoeconomic Analysis of Cilostazol for the Secondary Prevention of Cerebral Infarction
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概要
- 論文の詳細を見る
Background The antiplatelet agent, cilostazol, is known to reduce the risk of subsequent cerebral infarction. However, the cost effectiveness of such treatment in comparison to aspirin has not been studied. Methods and Results A Markov model was developed to calculate the health outcomes and associated costs for 65-year-old patients with cerebral infarction who were treated with 200mg/day cilostazol or 81mg/day aspirin. Cilostazol was more effective, but also more expensive than aspirin. Cilostazol would extend quality-adjusted life years (QALY) by 0.64, while increasing life-time costs by approximately \1.1 million. The incremental costeffectiveness ratio of cilostazol in comparison with aspirin was estimated to be \1.8 million per QALY. Conclusions The use of cilostazol to prevent recurrence of cerebral infarction appears to be cost effective.
- 社団法人日本循環器学会の論文
- 2006-03-20
著者
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Uchiyama Shinichiro
Department Of Neurology Tokyo Women's Medical University
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Uetsuka Yoshio
Medical Therapeutics And Hospital Management Tokyo Women's Medical University School Of Medicin
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Uchiyama Shinichiro
Department Of Neurology Neurological Insitute Tokyo Women's Medical University
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Inoue Tadao
Department of Pharmacy, St. Luke's International Hospital
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Kobayashi Makoto
Health Economics Research Group, Crecon Research & Consulting
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Inoue Tadao
Department Of Biotechnology Fukuyama University
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Inoue Tadao
Department Of Pharmacy St. Luke's International Hospital:medical Therapeutics And Hospital Mana
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Uchiyama Shinichiro
Department Of Neurology Neurological Institute Tokyo Women's Medical University School Of Medic
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Kobayashi Makoto
Health Economics Research Group Crecon Research & Consulting Inc.
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Uchiyama Shinichiro
Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University
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