競走馬の調教運動時における心臓突然死の病理学的および心電図学的検索
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概要
- 論文の詳細を見る
Five racehorses in apparently normal condition succumbed to sudden cardiac death (SCD) during or shortly after intensive training exercise. Cardiopathologic examination was performed. In 1 of the 5 horses, the use of an electrocardiogram (ECG) recording taken continuously for 440 sec enabled us to analyze some of the arrhythmias in the terminal event of SCD. The ECG tracing exhibited the R-on-T phenomenon following a pair of ventricular premature contractions (VPCs). The phenomenon rapidly degenerated into ventricular fibrillation, which led to cardiac arrest. In all 5 horses cardiopathologic examination revealed the following lesions: (i) foci of myocardial fibrosis in the right atrium located close to the sinoatrial (SA) node, (ii) fibrotic and/or fibroplastic changes in the upper portion of the interventricular septum, including the atrioventricular (AV) conduction system, and (iii) arterio-and arteriolosclerosis of the SA and AV node vessels. Pathogenetically, the process by which the focal lesions of myocardial ischemia secondary to vascular sclerosis progressed into fibrosis and/or fibroplasia could play a major role in the genesis of arrhythmias. Presumably the fibrotic and/or fibroplastic changes in the area or the AV bundle and its bundle branches are closely related to the onset or fatal ventricular arrhythmias such as VPCs, deteriorating into ventricular fibrillation. SCD in training and racing Thoroughbred horses appears to be due to arrhythmia.
- 社団法人日本獣医学会の論文
- 1999-08-25
著者
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Yoshihara Toyohiko
Dept. Tissue Physiol. Tokyo Univ. Agricul. and Technol
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TAJIMA Yoshio
Ritto Training Center
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YOSHIHARA Toyohiko
Ritto Training Center
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YOSHIHARA Toyohiko
Equine Research Institute
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Machida Noboru
Department Of Veterinary Clinical Oncology Faculty Of Agriculture Tokyo University Of Agriculture An
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Machida Noboru
Department Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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Yoshihara Toyohiko
Clinical And Pathobiology Division Equine Research Institute Japan Racing Association
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Yoshihara Toyohiko
Equine Research Institute Japan Racing Association (jra)
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Yoshihara Toyohiko
Equine Reseach Institute Japan Racing Association
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Yamamoto T
Animal Wellness Center Tokyo
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Kashida Yoko
Department Of Toxicology Azabu University School Of Veterinary Medicine
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KIRYU Keiji
Department of Veterinary Pathology, Tokyo University of Agriculture and Technology
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AMADA Akio
Blood Horse Training Center, JRA Foundation
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YAMAMOTO Takeshi
Racing Museum, JRA
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Amada A
Blood Horse Training Center Tokyo Jpn
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Amada Akio
Blood Horse Training Center
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Kiryu K
Tokyo Univ. Agriculture And Technol. Tokyo Jpn
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Kashida Yoko
Department Of Veterinary Pathology Tokyo University Of Agriculture And Technology
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Yoshihara T
Clinical And Pathobiology Division Equine Research Institute Japan Racing Association
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Yamamoto Takeshi
Racing Museum Jra
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桐生 啓治
Department of Veterinary Pathology, Tokyo University of Agriculture and Technology
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町田 登
Department of Veterinary Pathology, Tokyo University of Agriculture and Technology
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樫田 陽子
Department of Veterinary Pathology, Tokyo University of Agriculture and Technology
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