小児喘息患児のダニに対する免疫反応とその屋内塵中のダニ相について

概要

論文の詳細を見る
Immunological reactions were performed on asthmatic children living in and around Tokyo with the extract of house dust mite, Dermatophagoides pteronyssinus, as antigen. Mite fauna in house dusts of the patients was examined and relation between the mite fauna and immunological findings was studied. Higher than 70% or more positive rates were obtained in skin test and radioallergosorbent test (RAST) either to house dust or the mite antigens. On the other hand, passive hemagglutination test and double gel diffusion test against the mite extract were all negative. House dust was collected from the residences of 17 skin test and RAST positive patients and 10 negative asthmatic children. Pyroglyphid mites constituted 70-90% of the mite fauna and constitutional pattern of other mites did not differ in both groups. However, number of mites found in dusts per square meter for a week differed significantly (p<0.05). This study comfirms the importance of the house dust mite in children's asthma and shows that absolute number of mites in the dust plays an important role in the sensitization of children with substantial figure.
日本衛生動物学会の論文
1977-12-15