Syntheses of Substituted L- and D-Tryptophans
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概要
- 論文の詳細を見る
Several 5-substituted N_b-methoxycarbonyl-L- and -D-tryptophan derivatives were synthesized from proline by a new route involving electrochemical oxidation, as well as by the known procedures. Removal of the N_b-methoxycarbonyl group was accomplished by treatment with Me_3SiI in refluxing chloroform, then alkaline hydrolysis of the methyl esters afforded 5-substituted L- and D-tryptophans with high optical purities.
- 社団法人日本薬学会の論文
- 1984-06-25
著者
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石田 昭彦
Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.
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大石 篤郎
Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.
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中村 透
Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.,
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入江 邦彦
Organic Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.
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大石 篤郎
Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.
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中村 透
Organic Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.
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入江 邦彦
Drug Delivery System Institute Ltd. Building Of Research Institute For Bioscience The Science Univer
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