Metabolic Fate of 1-Ethynylcyclohexyl Carbamate. VI. Production of 1-Ethynylcyclohexane-trans-1,2-diol from 1-Ethynylcyclohexyl Carbamate in vitro.
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概要
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1-Ethynylcyclohexanol was perfused through rabbit liver, and the metabolites of it thus obtained were separated and identified by gas chromatography. A chief metabolite of the 1-ethynylcyclohexanol was ascertained to be 1-ethynylcyclohexane-1,2-diol, and this finding was well coincident with the result obtained from previous experiment. Furthermore, the production of 1-ethynylcyclohexane-1,4-diol from 1-ethynylcyclohexanol was also confirmed in this study, and the metabolic pathways of those were discussed.
- 公益社団法人日本薬学会の論文
- 1964-05-25
著者
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村田 敏郎
Shizuoka College of Pharmacy
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村田 敏郎
Faculty of Pharmaceutical Sciences, Kumamoto University
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江藤 祥子
Faculty of Pharmaceutical Sciences, Kumamoto University
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淵上 節子
Faculty of Pharmaceutical Sciences, Kumamoto University
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江藤 祥子
Faculty Of Pharmaceutical Sciences Kumamoto University
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淵上 節子
Faculty Of Pharmaceutical Sciences Kumamoto University
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