Zingiber mioga ROSCOEの薬理学的研究 : Thiopental睡眠時間ならびに脳内自己刺激行動に及ぼす影響
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概要
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The pharmacological effects of water-soluble and insoluble fractions extracted from Zingiber mioga ROSCOE were examined in mice and rats. In mice, Fr-W_1,Fr-2 and Fr-W_4 in water-soluble fraction significantly prolonged the sleeping time after thiopental Na administration. Intracranial self-stimulation behavior in rats was also depressed by Fr-W_1 and Fr-W_4. These results suggest the possible existence of some substances that exert central nervous depressive action in these fractions.
- 公益社団法人日本薬学会の論文
- 1980-04-25
著者
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西岡 五夫
九州大学薬学部
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川崎 博己
岡山大院医歯薬学総合臨床薬学
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市丸 保幸
第一薬科大学
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内門 昭久
第一薬科大学
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市丸 保幸
グラクソスミスクライン(株)cns部
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川崎 博己
宮崎医科大学
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森山 峰博
第一薬科大学薬理学教室
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