DIFFERENCE BETWEEN MAGNESIUM AND MANGANESE IONS IN MODIFICATION OF EFFECT OF CATECHOLAMINE ON ADENYLATE CYCLASE SYSTEM IN EHRLICH ASCITES TUMOR CELLS
スポンサーリンク
概要
- 論文の詳細を見る
Involvement of divalent cations was examined in the activation of catecholaminesensitive adenylate cyclase in Ehrlich ascites tumor cells. In the presence of various concentrations of either Mg^<2+> or Mn^<2+>, both basal and norepinephrine-stimulated adenylate cyclase activities were measured. Both activities were gradually increased with the increase in Mg^<2+> concentration. On the other hand, with Mn^<2+>, both activities were maximum at the low (2.5mM) concentration, and decreased at the higher concentrations, the decrease being marked in the norepinephrine-stimulated activity. Similar difference between the two divalent cations was also observed in the effect on the binding of the β-adrenergic ligand to the membrane receptor.
- 公益社団法人日本薬学会の論文
著者
-
Kitamura Yoko
Department Of Cardiology Nagoya University Graduate School Of Medicine
-
Kitamura Yoko
Department Of Physiological Chemistry Institute Of Pharmaceutical Sciences Hiroshima University Scho
-
KUROKAWA TOMONORI
Department of Physiological Chemistry, Hiroshima University School of Medicine
-
Ishibashi Sadahiko
Department Of Physiological Chemistry Faculty Of Medicine Hiroshima University
-
MORIUCHI MIDORI
Department of Physiological Chemistry, Institute of Pharmaceutical Sciences, Hiroshima University Sc
-
Kurokawa Tomonori
Department Of Physiological Chemistry Hiroshima University School Of Medicine
-
Kurokawa Tomonori
Department Of Physiological Chemistry Institute Of Pharmaceutical Sciences Hiroshima University Scho
-
Ishibashi Sadahiko
Department Of Physiological Chemistry Institute Of Pharmaceutical Sciences Hiroshima University Scho
-
Moriuchi Midori
Department Of Physiological Chemistry Institute Of Pharmaceutical Sciences Hiroshima University Scho
関連論文
- OJ-062 The 4G/5G Polymorphism in the Plasminogen Activator Inhibitor-I Gene is Associtated With Alterations in LDL Particle Size Distribtution(Lipid Disorders 1 (H) : OJ8)(Oral Presentation (Japanese))
- Association between Common Polymorphism in the Promoter Region of the Microsomal Triglyceride Transfer Protein Gene and LDL Particle Size
- Inhibition of COX-2 Prevents Hypertension and Proteinuria Associated with a Decrease of 8-lso-PGF2α Formation in L-NAME-Treated Rats
- Decavanadate Inhibits the Cell-Free Activation of Neutrophil NADPH Oxidase without Affecting Tyrosine Phosphorylation
- Sphingosine Inhibition of NADPH Oxidase Activation in a Cell-Free System
- Differences in Mechanisms for Cell-Free NADPH Oxidase Activation between Arachidonate and Sodium Dodecyl Sulfate
- BRAIN ADENYLATE CYCLASE INHIBITION BY BENZODIAZEPINES
- CHARACTERIZATION OF HETEROLOGOUS DESENSITIZATION OF RAT RETICULOCYTE ADENYLATE CYCLASE SYSTEM
- INHIBITION OF BRAIN ADENYLATE CYCLASE BY BARBITURATES THROUGH THE EFFECT ON THE INTERACTION BETWEEN GUANINE NUCLEOTIDE-BINDING STIMULATORY REGULATORY PROTEIN AND CATALITIC UNIT
- INTERACTIONS BETWEEN VARIOUS LIGANDS IN THE ACTIVATION AND DESENSITIZATION OF ADENYLATE CYCLASE SYSTEM
- Properties of NADPH Oxidase in Specific Granule-Rich Fraction Prepared from Guinea Pig Neutrophils
- Hepatic Amyloidosis Manifesting Severe Intrahepatic Cholestasis
- Mechanism for the Inhibitory Effect of a Seleno-Organic Compound, Ebselen, and Its Analogues on Superoxide Anion Production in Guinea Pig Polymorphonuclear Leukocytes
- INHIBITION OF SUPEROXIDE ANION PRODUCTION IN GUINEA PIG POLYMORPHONUCLEAR LEUKOCYTES BY A SELENO-OR-GANIC COMPOUND, EBSELEN
- DIFFERENCE BETWEEN MAGNESIUM AND MANGANESE IONS IN MODIFICATION OF EFFECT OF CATECHOLAMINE ON ADENYLATE CYCLASE SYSTEM IN EHRLICH ASCITES TUMOR CELLS
- Differences in the Expression of Glucose Transporter Protein Isoforms in Human Retinoblastoma Cell Lines
- Ca^/CALMODULIN EFFECTS ON cAMP RESPONSE IN CULTURED CHICK CILIARY EPITHELIAL CELLS
- ISOFORMS OF GLUCOSE TRANSPORTER IN THE IRIS-CILIARY BODY
- LEARNING CURVE FOR ENDOSCOPIC SUBMUCOSAL DISSECTION OF LARGE COLORECTAL TUMORS
- MODE OF INTERACTION BETWEEN FORSKOLIN AND MANGANESE ION IN ACTIVATING CATALYTIC UNIT OF ADENYLATE CYCLASE FROM RAT BRAIN
- IN VITRO DEMONSTRATION OF DECREASED GLUCOSE OXIDATION IN BRAIN OF EXPERIMENTALLY DIABETIC RAT AND RECOVERY BY INSULIN
- The Mechanism of Insulin Action on Hexokinase Isozymes
- Involvement of the inhibitory GTP-binding regulatory protein and a low-affinity benzodiazepine receptor in the inhibitory effect of diazepam on rat brain adenylate cyclase system.
- Sphingosine Inhibition of NADPH Oxidase Activation in a Cell-Free System.