IN VITRO DEMONSTRATION OF DECREASED GLUCOSE OXIDATION IN BRAIN OF EXPERIMENTALLY DIABETIC RAT AND RECOVERY BY INSULIN
スポンサーリンク
概要
- 論文の詳細を見る
In the course of studies on glucose metabolism in the brain under the condition with excessive supply of glucose, ^<14>CO_2 production from glucose-^<14>C was examined by incubating the homogenate of the brain from control and streptozotocin-diabetic rats. The production was markedly decreased in the brain homogenate of the diabetic rats as compared with that of control rats. Administration of insulin in the diabetic rats restored the glucose oxidation activity to the control level, but about 30 min was necessary for the restoration. No difference was found between glucose-1-^<14>C and glucose-6-^<14>C in the change in ^<14>CO_2 production by the brain homogenate from diabetic rats before and after insulin treatment.
- 公益社団法人日本薬学会の論文
著者
-
Ishibashi Sadahiko
Department Of Physiological Chemistry Faculty Of Medicine Hiroshima University
-
Ishibashi Sadahiko
Department Of Physiological Chemistry Institute Of Pharmaceutical Sciences Hiroshima University Scho
-
Shima Ikuyo
Department Of Physiological Chemistry Institute Of Pharmaceutical Sciences Hiroshima University Scho
-
KANAGUCHI SHIGEKO
Department of Physiological Chemistry, Institute of Pharmaceutical Sciences, Hiroshima University Sc
-
Kanaguchi Shigeko
Department Of Physiological Chemistry Institute Of Pharmaceutical Sciences Hiroshima University Scho
関連論文
- Decavanadate Inhibits the Cell-Free Activation of Neutrophil NADPH Oxidase without Affecting Tyrosine Phosphorylation
- Sphingosine Inhibition of NADPH Oxidase Activation in a Cell-Free System
- Differences in Mechanisms for Cell-Free NADPH Oxidase Activation between Arachidonate and Sodium Dodecyl Sulfate
- BRAIN ADENYLATE CYCLASE INHIBITION BY BENZODIAZEPINES
- CHARACTERIZATION OF HETEROLOGOUS DESENSITIZATION OF RAT RETICULOCYTE ADENYLATE CYCLASE SYSTEM
- INHIBITION OF BRAIN ADENYLATE CYCLASE BY BARBITURATES THROUGH THE EFFECT ON THE INTERACTION BETWEEN GUANINE NUCLEOTIDE-BINDING STIMULATORY REGULATORY PROTEIN AND CATALITIC UNIT
- INTERACTIONS BETWEEN VARIOUS LIGANDS IN THE ACTIVATION AND DESENSITIZATION OF ADENYLATE CYCLASE SYSTEM
- Properties of NADPH Oxidase in Specific Granule-Rich Fraction Prepared from Guinea Pig Neutrophils
- Mechanism for the Inhibitory Effect of a Seleno-Organic Compound, Ebselen, and Its Analogues on Superoxide Anion Production in Guinea Pig Polymorphonuclear Leukocytes
- INHIBITION OF SUPEROXIDE ANION PRODUCTION IN GUINEA PIG POLYMORPHONUCLEAR LEUKOCYTES BY A SELENO-OR-GANIC COMPOUND, EBSELEN
- DIFFERENCE BETWEEN MAGNESIUM AND MANGANESE IONS IN MODIFICATION OF EFFECT OF CATECHOLAMINE ON ADENYLATE CYCLASE SYSTEM IN EHRLICH ASCITES TUMOR CELLS
- Differences in the Expression of Glucose Transporter Protein Isoforms in Human Retinoblastoma Cell Lines
- ISOFORMS OF GLUCOSE TRANSPORTER IN THE IRIS-CILIARY BODY
- MODE OF INTERACTION BETWEEN FORSKOLIN AND MANGANESE ION IN ACTIVATING CATALYTIC UNIT OF ADENYLATE CYCLASE FROM RAT BRAIN
- IN VITRO DEMONSTRATION OF DECREASED GLUCOSE OXIDATION IN BRAIN OF EXPERIMENTALLY DIABETIC RAT AND RECOVERY BY INSULIN
- The Mechanism of Insulin Action on Hexokinase Isozymes
- Involvement of the inhibitory GTP-binding regulatory protein and a low-affinity benzodiazepine receptor in the inhibitory effect of diazepam on rat brain adenylate cyclase system.
- Sphingosine Inhibition of NADPH Oxidase Activation in a Cell-Free System.