EFFECT OF COLCHICINE AND CYTOCHALASIN B ON THE SECRETION OF PROTEOCHONDROITIN SULFATE AND PROTEINFREE CHONDROITIN SULFATE SYNTHESIZED IN CARTILAGE SLICES
スポンサーリンク
概要
- 論文の詳細を見る
A possible role of microtubules and microfilaments in the secretion process of proteoglycan and protein-free glycosaminoglycan synthesized in slices of bovine nasal cartilage was examined by using colchicine as an antimicrotubular agent, cytochalasin B as a microfilament-modifying agent, and 4-methylumbelliferyl β-D-xyloside as an artificial initiator of glycosaminoglycan. The present study suggested that the microtubule system was partly involved in the secretion of proteochondroitin sultate and protein-tree chondroitin sultate synthesized in chondrocytes. The microfilament system did not have any direct effect on this secretion process.
- 公益社団法人日本薬学会の論文
著者
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Honda Atsushi
Department of Cardiology, Tokyo Women's Medical University
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Honda Atsushi
Department Of Biochemistry Tokyo College Of Pharmacy
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MORI YO
Department of Biochemistry, Tokyo College of Pharmacy
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Mori Yo
Department Of Biochemistry Tokyo College Of Pharmacy
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Murakami Naoto
Department Of Biochemistry Tokyo College Of Pharmacy
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Takakubo Fumie
Department Of Biochemistry Tokyo College Of Pharmacy
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