OCCURRENCE OF LOOSELY BOUND MERCURY IN THE BLOOD OF GUINEA PIG TREATED WITH METHYLMERCURIC CHLORIDE
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概要
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Guinea pigs were given ^<203>Hg-labeled methylmercuric chloride or mercuric chloride and then the distribution of mercury in the blood, brain and liver was investigated. The methylmercury in the blood and brain was extracted with a chloroform-methanol mixture. Most of the extractable mercury from the blood was detected in the proteolipid fraction by further fractionation. The mercury in the chloroform-methanol extract was also dialyzable against the same solvent. These findings suggest the occurrence of loosely bound mercury in the blood after administration of methylmercury.
- 公益社団法人日本薬学会の論文
著者
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UDA Yutaka
Department of Health Chemistry, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy a
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Uda Yutaka
Department Of Chemical Toxicology Medical Research Institute Tokyo Medical And Dental University
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Nakazawa Yasuo
Department Of Chemical Toxicology Medical Research Institute Tokyo Medical And Dental University
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