Synthesis and Absolute Configuration of (+)-threo-1-Hydroxy-2-(isopropylamino)-[10]-paracyclophane
スポンサーリンク
概要
- 論文の詳細を見る
threo-1-Hydroxy-2-(isopropylamino)-[10]-paracyclophane (1) was prepared and resolved into one enantiomer. The absolute configuration of 1 was deduced from the analysis of circular dichroism (CD) spectra using Snatzke's sector rule and induced CD of Cu(su)_2(ip)_2 and Pr(DPM)_3. Intrinsic sympathomimetic activity of 1 and threo-and erythro-1-(4-tolyl)-2-isopropylamino-1-propanol were tested on the isolated guinea pig heart.
- 公益社団法人日本薬学会の論文
- 1976-08-25
著者
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萩下 山治
Shionogi Research Laboratories Shionogi & Co. Ltd.
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栗山 馨
Shionogi Research Laboratories Shionogi And Co.
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