Studies on Pentenomycins. IV. Preparation and Antimicrobial Activities of Pentenomycin Derivatives

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概要

• 論文の詳細を見る

• Eleven acyl and alkyliden derivatives of pentenomycin I (I) were synthesized for obtaining an improved antibiotic. All derivatives synthesized showed same order of or improved antimicrobial activity than the natural antibiotic. Among these derivatives, 2-bromo-4,5,6-triacetylpentenomycin I (XIV) showed strongest antimicrobial activity.

• 社団法人日本薬学会の論文
• 1974-09-25

著者

• 山口 東太郎

  Microbiological Research Laboratory, Tanabe Seiyaku Co., Ltd.

• 伊藤 幸雄

  Drug Delivery System Institute Ltd.

• 海野 喜実夫

  Microbial Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.

• 伊藤 幸雄

  Microbial Chemistry Research Laboratory, Tanabe Seiyaku Co., Ltd.

• 海野 喜実夫

  Microbial Chemistry Research Laboratory

• 山口 東太郎

  Microbiological Research Laboratory Tanabe Seiyaku Co. Ltd

関連論文

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• New Methods Suitable for Large-Scale Preparation of Sialoglycosides
• Studies on Pentenomycins. IV. Preparation and Antimicrobial Activities of Pentenomycin Derivatives
• Studies on Pentenomycins. II. The Structures of Pentenomycin I and II, New Antibiotics
• Naematolin, a New Biologically Active Substance produced by Naematoloma fasciculare (Fr.) KARST
• Studies on Pentenomycins. III. The X-Ray Crystal Structure Analysis of Monobromopentenomycin Triacetate
• Studies on biologically Active Halogenated Compounds. IV. Synthesis and Antibacterial Activity of Fluorinated Quinoline Derivatives
• Studies on biologically Active Haloganenated Compounds. III. Synthesis and Antibacterial Activity of 7-Fluoromethyl-1,8-naphthyridine and Quinoline Derivatives
• Further Studies on Synthesis and Antimicrobial Activity of Thioformin Analogues

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