Synthesis and Absolute Configurations of the Cytotoxic Polyacetylenes Isolated from the Callus of Panax ginseng
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概要
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Panaxacol (1) and dihydropanaxacol (2), cytotoxic polyacetylenes isolated from the callus of Panax ginseng, were synthesized starting from D-(-)-diethyl tartrate. The absolute configuration of 1 was determined to be 9R, 10R and the absolute configuration at C-3 of 2 was tentatively assigned as 3S by the application of the R(+)-α-methoxy-α-(trifluoromethyl)phenylacetyl (MTPA) method.
- 1990-06-25
著者
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竹内 直樹
Showa College Of Pharmaceutical Sciences
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藤本 康雄
日本大学薬学部
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Takeuchi N
Showa College Of Pharmaceutical Sciences
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藤本 康雄
日本大学 薬
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佐藤 美鶴
昭和薬科大学
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桐沢 誠
College of Pharmacy, Nihon University
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佐藤 美鶴
Showa College of Pharmaceutical Sciences
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藤本 康雄
Nihon University, College of Pharmacy
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桐沢 誠
Nihon University, College of Pharmacy
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桐沢 誠
College Of Pharmacy Nihon University
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