Synthesis of Pyridazine Derivatives. IX. Nitration of 3,4-Dimethylpyridazine N-Oxide Derivatives.
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概要
- 論文の詳細を見る
Nitration of 3,4-dimethyl (Ia), 6-chloro-3,4-dimethyl (Ib), 6-methoxy-3,4-dimethylpyridazine 2-oxide (Ic), 3,4-dimethyl (Id) and 3-methylpyridazine 1-oxide (Ie) was examined and it was proved that Ia, Ib, Ic and Ie afforded γ-nitropyridazine N-oxides (IIa〜IIe), whereas Id in which γ-position was substituted gave α-nitro N-oxide (IId). All of these nitro derivatives were derived to aminopyridazines (IIIa〜IIIe) by catalytic reduction over Raney-nickel in methanol or over palladium-charcoal in dilute hydrochloric acid. Ultraviolet spectra of several aminopyridazines are also given.
- 公益社団法人日本薬学会の論文
- 1963-06-25
著者
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中込 孟也
Research Department, Pharmaceutical Division, Sumitomo Chemical Co., Ltd.
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中込 孟也
Research And Development Center Pharmaceuticals Division Sumitomo Chemical Co. Ltd.
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- Synthesis of Pyridazine Derivatives. XIII. Synthesis of N^1-(2-methyl-3-oxo-2,3-dihydro-4-pyridazinyl)-sulfanilamide Derivatives.
- Conversion of Acylamidopenicillins to Phosphoramidopenicillins, and Removal of Their Phosphoryl Side Chain
- Synthesis of Pyridazine Derivatives. XIV. On the Methylation of 4-Amino-3 (2H) pyridazinone Derivatives
- Synthesis of Pyridazine Derivatives. IX. Nitration of 3,4-Dimethylpyridazine N-Oxide Derivatives.
- Synthesis of Pyridazine Derivatives. VIII. N-Oxidation of 3,4-Dimethylpyridazine Derivatives.
- Bemerkung zur Nitrierung des 1,2,3,4-Tetrahydroisochinolins und seiner Derivate.
- Uber die Umlagerung von 5-Nitroisochinolin-N-Oxyd mittels Tosylchlorids.