Synthesis of Related Compounds of Thiosemi-carbazide. IV. 1-(1,3,4-Thiadiazol-2-yl)-2-pyrazolin-5-one and Tetrazolo [4,5-a]-1,3,4-thiadiazole Derivatives.
スポンサーリンク
概要
- 論文の詳細を見る
1) 1-(5-R-1,3,4-Thiadiazol-2-yl)-3-methyl-4-R'-2-pyrazolin-5-one (R'=H, iso-C_3H_7) (III) were synthesized starting with 2-hydrazino-5-R-1,3,4-thiadiazole (I : R=CH_3,C_2H_5,n-C_3H_7,iso-C_4H_9,C_6H_5), and reacting them with ethyl acetoacetate or ethyl 3-acetyliso-valerate to form 5-R-1,3,4-thiadiazolylhydrazone (II). 2) 2-R-Tetrazolo [4,5-a]-1,3,4-thiadiazole, compound analogous to 8-azaguanine, were synthesized by the reaction of 2-hydrazino-5-R-1,3,4-thiadiazole (I) with sodium nitrite in diluted acetic acid.
- 公益社団法人日本薬学会の論文
- 1958-08-15
著者
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金岡 又雄
Research Institute for WAKAN-YAKU (Oriental Medicines), Toyama Medical and Pharmaceutical University
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金岡 又雄
Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University
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金岡 又雄
Pharmaceutical Faculty University Of Toyama
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- Synthesis of Related Compounds of Thiosemi-carbazide. IV. 1-(1,3,4-Thiadiazol-2-yl)-2-pyrazolin-5-one and Tetrazolo [4,5-a]-1,3,4-thiadiazole Derivatives.