Synthetic Inhibitors of DNA Topoisomerase I and II
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概要
- 論文の詳細を見る
A new type of synthetic inhibitor of DNA topoisomerase I and II was examined and several of these derivatives exhibited strong dual activity against these enzymes. This series of compounds showed high cytotoxic activities against cancer cells, but only a limited number of compounds showed any noticeable activity in an in vivo test against murine P388. Non-specific toxicity was observed in the in vivo tests.
- 公益社団法人日本薬学会の論文
- 1999-01-15
著者
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Katayama H
Niigata Coll. Pharmacy Niigata Jpn
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Katayama Hajime
Niigata College Of Pharmacy
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Kaneko Kimiyoshi
Niigata College of Pharmacy
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Kanada Ken
Pharmaceutical Laboratories Kissei Pharmaceuticalco. Ltd
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Kaneko K
Niigata College Of Pharmacy
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Katayama H
Niigata College Of Pharmacy
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KAWADA Yusuke
Niigata College of Pharmacy
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OSHIYAMA Takamitsu
Niigata College of Pharmacy
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TAKATSU Noriyuki
Niigata College of Pharmacy
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TAGAWA Naoyuki
Niigata College of Pharmacy
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Kawada Y
Niigata College Of Pharmacy
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Oshiyama T
Niigata College Of Pharmacy
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