Preparation of Naphthoquinone Derivatives from Plumbagin and Their Ichthyotoxicity
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概要
- 論文の詳細を見る
Various naphthoquinone derivatives were prepared from a natural product, 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin); these were mostly substituted at C-3 through carbon-carbon bond formation mediated by a metal-based oxidant such as lead tetraacetate in the presence of various carboxylic acids. The halogenated compounds showed stronger ichthyotoxicity than plumbagin, but other derivatives were less active.
- 公益社団法人日本薬学会の論文
- 1997-03-15
著者
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比嘉 松武
Univ. Ryukyus Okinawa Jpn
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Higa Matsutake
College Of Science University Of The Ryukyus
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荻原 和仁
琉球大学理学部
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OGIHARA Kazuhito
Department of Chemistry, College of Science, University of the Ryukyus
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YAMASHIRO Rieko
Department of Chemistry, College of Science, University of the Ryukyus
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HIGA Matsutake
Department of Chemistry, College of Science, University of the Ryukyus
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YOGI Seiichi
Department of Chemistry, College of Science, University of the Ryukyus
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与儀 誠一
Univ. Ryukyus Okinawa Jpn
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Yogi S
College Of Science University Of The Ryukyus
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Yamashiro Rieko
Department Of Chemistry College Of Science University Of The Ryukyus
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