Isolation of Six New Flavonoids from Melicope triphylla
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概要
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Six new flavonoids—5-hydroxy-3,8-dimethoxy-3′,4′:6,7-bismethylenedioxyflavone (1), 3,3′,4′,5-tetramethoxy-7-(3-methylbut-2-enyloxy)flavone (2), 7-(2-hydroxy-3-methylbut-3-enyloxy)-3,3′,4′,5-tetramethoxyflavone (3), 7-(2-hydroxy-3-methylbut-3-enyloxy)-3,5-dimethoxy-3′,4′-methylenedioxyflavone (4), 7-(2-hydroxy-3-methylbut-3-enyloxy)-3,3′,4′,5,8-pentamethoxyflavone (5), and 7-(2-hydroxy-3-methylbut-3-enyloxy)-3,5,8-trimethoxy-3′,4′-methylenedioxyflavone (6)—were isolated from the leaves of Melicope triphylla. In addition, six already known flavonoids were also detected: 5-hydroxy-3,6,7-trimethoxy-3′,4′-methylenedioxyflavone (7), 5,7-dihydroxy-3,3′,4′,8-tetramethoxyflavone (8), 4′,5-dihydroxy-3,3′,7,8-tetramethoxyflavone (9), 3,5,6,7,8-pentamethoxy-3′,4′-methylenedioxyflavone (10), 3,5,6,7-tetramethoxy-3′,4′-methylenedioxyflavone (11), and 3,3′,4′,5,6,7,8-heptamethoxyflavone (12). The structures of the new compounds were established by spectroscopic methods. Compound 2 displayed ichthyotoxic activity against Japanese killifish (medaka in Japanese) (Oryzias latipes var.) at 10 ppm.
- 公益社団法人 日本薬学会の論文
著者
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Higa Matsutake
College Of Science University Of The Ryukyus
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Imamura Megumi
College of Science, University of the Ryukyus
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Ogihara Kazuhito
College of Science, University of the Ryukyus
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Suzuka Toshimasa
College of Science, University of the Ryukyus
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Ogihara Kazuhito
College Of Science University Of The Ryukyus
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Higa Matsutake
Univ. Ryukyus Okinawa Jpn
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Shimoji Kanae
College of Science, University of The Ryukyus
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Higa Matsutake
College of Science, University of the Ryukyus
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