Penetration of Outer Layered Particles of Agglomerate into Inner Intersticies of Agglomerate during Spherical Agglomeration in Liquid
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概要
- 論文の詳細を見る
Layering agglomeration of aluminum lake particles, i.e. a fine reddish pigment, was conducted by depositing them on a cored agglomerate of lactose prepared by the wet spherical agglomeration technique with a bridging liquid, i.e. water, in a dispersing medium, i.e. chloroform, under agitation. The layered agglomerates were spheronized and compacted during agglomeration. The processes of layering agglomeration and compaction are as described by the selective coalescence mechanism proposed by Kapur and a modified Kawakita's equation. It was newly found that the aluminium lake particles layered on the surface of a core agglomerate penetrated gradually into the inside of core agglomerates during agglomeration. The penetration behaviors of aluminum lake particles were represented by their relative movement coefficients, found by measuring their distributions in the agglomerate with a color measuring system. The mechanism of penetration of aluminum lake particles was discussed by referring to the tapping processes of aluminum lake and lactose powders in liquid and air.
- 公益社団法人日本薬学会の論文
- 1997-02-15
著者
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TAKEUCHI Hirofumi
Department of Pharmaceutical Engineering, Gifu Pharmaceutical University
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Niwa K
Gifu Univ. School Of Medicine Gifu Jpn
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Hino Tomoaki
Department Of Nuclear Engineering Hokkaido University
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KAWASHIMA YOSHIAKI
Pharmaceutical Engineering Laboratory, Gifu Pharmaceutical University
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NIWA Kouji
Pharmaceutical Engineering, Gifu Pharmaceutical University
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TAKEUCHI Hirofumi
Pharmaceutical Engineering, Gifu Pharmaceutical University
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HINO Tomoaki
Pharmaceutical Engineering, Gifu Pharmaceutical University
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