<Abstract of published report>Improvements in flowability and compressibility of pharmaceutical crystals for direct tabletting by spherical crystallization with a two-solvent system.
スポンサーリンク
概要
著者
-
TAKEUCHI Hirofumi
Department of Pharmaceutical Engineering, Gifu Pharmaceutical University
-
Cui F
Shenyang Pharmaceutical Univ. Shenyang Chn
-
Hino Tomoaki
Department Of Nuclear Engineering Hokkaido University
関連論文
- Retention and Desorption of Hydrogen and Helium in Inner Wall Material Used for The Large Helical Device (LHD) : Simulation experiments using a glow discharge apparatus
- Retention and Desorption of Discharge Gases in Wall Materials Used for Large Helical Device
- Slow Release of Tetracycline from a Mucoadhesive Complex with Sucralfate for Eradication of Helicobacter pylori
- Development of Agglomerated Crystals of Ascorbic Acid for Direct Tableting by Spherical Crystallization Technique and Evaluation of Their Compactibilities.
- Formulation Design of Ointment Base Suitable for Healing of Lesions in Treatment of Bedsores.
- Mucoadhesive Liposomes : Physicochemical Properties and Release Behavior of Water-Solubule Drugs from Chitosan-Coated Liposomes.
- Modification of the Physicochemical Properties of Minocycline Hydrochloride Ointment with Cyclodextrines for Optimum Treatment of Bedsore.
- Formulation Design of Ointment Base Suitable for Healing of Lesions in Treatment of Bedsores
- Compaction Properties of Composite Particles Consisting of Lactose with Sodium Alginate Prepared by Spray-Drying.
- Formulation and in vivo evaluation of w/o/w emulsion encapsulating Epirubicin hydrochloride for the transcatheter arterial embolization therapy for hepatocellular carcinoma.
- Prolonged Circulation Time of Doxorubicin-loaded Liposomes Coated with a Modified Polyvinyl Alcohol after Intravenous Injection in Rats.
- Mixed Base of Hydrophilic Ointment and Purified Lanolin to Improve the Drug Release Rate and Absorption of Water of Minocycline Hydrochloride Ointment for Treatment of Bedsores.
- Comparison of Lipiodol Water-in-Oil-in-Water Emulsion and Oil-in-Water Emulsion : Acute Toxicity and Deposition in Liver after Hepatic Arterial Administration in Rats.
- Pulmonary Delivery of Insulin with Nebulized DL-Lactide/Glycolide Copolymer(PLGA) Nanospheres to Prolong Hypoglycemic Effect.
- Modification of the Physicochemical Properties of Minocycline Hydrochloride Ointment with Cyclodextrines for Optimum Treatment of Bedsore
- Surface-modified Antiasthmatic Dry Powder Aerosols Inhaled Intratracheally Reduce the Pharmacologically Effective Dose.
- A New Powder Design Method to Improve Inhalation Efficiency of Pranlukast Hydrate Dry Powder Aerosols by Surface Modification with Hydroxypropylmethylcellulose Phthalate Nanospheres.
- Preparation of Spherically Granulated Crystals of Waxy Drug(Tocopherol Nicotinate) for Direct Tableting by Spherical Crystallization Technique.
- Spray-dried Composite Particles of Lactose and Sodium Alginate for Direct Tabletting and Controlled Releasing.
- Design of Inhalation Dry Powder of Pranlukast Hydrate to Improve Dispersibility by the Surface Modification with Light Anhydrous Silicic Acid(AEROSIL 200)
- Effect of Surface Morphology of Carrier Lactose on Dry Powder Inhalation Property of Pranlukast Hydrate.
- Particle Design of Wogon Extract Dry Powder for Inhalation Aerosols with Granulation Method.
- Helium Retention of 316L Stainless Steel Used for The First Wall of The Large Helical Device (LHD)
- Engineering of poly(DL-lactic-co-glycolic acid) nanocomposite particles for dry powder inhalation dosage forms of insulin with the spray-fluidized bed granulating system
- Tabletting of Solid Dispersion Particles Consisting of Indomethacin and Porous Silica Particles
- A new spherically agglomerated drug composite system with lactose for dry powder inhalation
- Design of rolipram-loaded nanoparticles : comparison of two preparation methods.
- Biodegradable Nanoparticles for Targeted Ddrug Delivery in Treatment of Inflammatory Bowel Disease.
- Mucoadhesive nanoparticulate systems for peptide drug delivery.
- Evaluation of the anti-tumour activity of liposomal doxorubicin coated with hydrophilic polymers in tumour-bearing mice.
- Surface Modification of Liposomes with Various Hydrophilic Polymers Bearing Hydrophobic Anchors and Their Circulation Properties.
- Preparation of a Gel-Forming Ointment Base Applicable to the Recovery Stage of Bedsore and Clinical Evaluation of a Treatment Method with Different Ointment Bases Suitable to each Stage of Bedsore.
- Evaluation of ciruclation profiles of liposomes coated with hydrophilic polymers having different molecular weights in rats.
- Passive Tartgeting of Doxorubicin with Polymer Coated Liposomes in Tumor Bearing Rats.
- Passive Targeting of Doxorubicin with Polymer Coated Liposomes in Tumor Bearing Rats
- In Vitro Inhalation Behavior of Spherically Agglomerated Steroid Particles with Carrier Lactose.
- Temperature-Induced Crystallization and Compactibility of Spray Dried Composite Particles Composed of Amorphous Lactose and Various Types of Water-Solbule Polymer.
- Mucoadhesive DL-Lactide/Glycolide Copolymer Nanospheres coated with Chitosan to Improve Oral Delivery of Elcatonin.
- Formulation of Gel-Formation Ointments with Hydrophilic Polymers for Treatment of Recovery Stage of Bedsore.
- Drug Release from Water-in-Oil-in-Water Multiple Emulsoins In Vitro. : Effects of the Addition of Hydrophilic Surfactants to the Internal Aqueous Compartment on the Release Rate of Water-soluble Drug.
- Improvement of the stability of water-in-oil-in-water multiple emulsions by the addition of surfactants in the internal aqueous phase of the emulsions.
- Drug Release from the Water-in-Oil-in-Water Multiple Emulsion in Vitro. II. : Effects of the Addition of Hydrophilic Surfactants to the Internal Aqueous Compartment on the Release Rate of Secretin.
- Hydrogen and Helium Desorptions from B4C Overlaid Graphite and Isotropic Graphite
- Model for Hydrogen Retention and Chemical Sputtering of Boron-Carbon Plasma Facing Material
- Conditionings for Boron-Carbon Plasma Facing Wall
- Gas Desorption of Inner Coating Materials Used for Cathode Ray Tube after Electron Beam Irradiation (第45回真空に関する連合講演会プロシーディングス--2004年10月27日〜29日,大阪)
- Morphology and Hydrogen Retention of Carbon Dust Produced by Hydrogen Discharges in JT-60 (第44回真空に関する連合講演会プロシーディングス--2003年11月12日〜14日,東京)
- Lafferty Gauge for Pressure Measurement of Extremely High Vacuum
- Multipole Gauge for Pressure Measurement of Extremely High Vacuum
- Gas Desorption of Inner Coating Materials Used for Cathode Ray--Tube Effect of exposure time in the atmosphere on gas desorption (第44回真空に関する連合講演会プロシーディングス--2003年11月12日〜14日,東京)
- Desorption behavior of H2O from isotropic graphites dipped in water
- Hydrogen desorption behavior of aluminium materials used for extremely high vacuum chamber
- Dependence of Incident Angle of Surface Morphology of Polycrystalline Copper after Helium Ion Irradiation
- Deuterium Retention of Vanadium Alloy, V-4Cr-4Ti
- Helium Gas Permeability of Low Activation SiC/SiC Composite
- Gas-Desorption Properties of Inner Coating Materials Used for Cathode-Ray Tube : Effect of Water Glass Component of Inner Coating Material on Gas Desorption
- Deuterium Retention of Low Activation Ferritic Steel F82H
- Polymer Coating of Liposomes with a Modified Polyvinyl Alcohol and Their Systemic Circulation and RES Uptake in Rats.
- Evaluation of Acute Toxicity of Epirubicin Hydrochloride-encapsulating w/o/w Emulsion Administered to Rat for the Transcatheter Embolization Therapy for Hepatocellular Carcinoma.
- Formulation of w/o/w lipiodol emulsion encapsulating epirubicin hydrochloride for the transcatheter arterial embolization therapy for hepatocellular carcinoma.
- Control of Cimetidine Crystal Forms Using Colloidal Silica in Pharmaceutical Preparation Process.
- In Vitro and In Vivo Evaluation of Mini-depot Tablet Prepared Using Poly(DL-lactide-co-glycolide)nanoparticles as Retardant Material.
- Utilization of Poly(DL-lactide-co-glycolide)nanoparticles for Preparation of Mini-depot Tablets by Direct Compression.
- Further Application of a Modified Spontaneous Emulsification Solvent Diffusion Method to Various Types of PLGA and PLA Polymers for Preparation of Nanoparticles.
- Evaluation of Poly(DL-lactide-co-glycolide)Nanoparticles as Matrix Material for Direct Compression.
- Evaluation of poly(DL-lactide-co-glycolide) nanoparticles as matrix material for direct compression
- Influence of the Degrees of Hydrolyzation and Polymerization of Poly(vinylalchol)on the Preparation and Properties of Poly(DL-lactide-co-glycolide)nanoparticle.
- Biodegradable submicron carriers for peptide drugs : Preparation of DL-lactide/glycolide copolymer(PLGA)nanospheres with nafarelin acetate by a novel emulsion-phase separation method in an oil system.
- Drug Releasing Properties and Tensile Strength of Dry-Coated Tablets Prepared with Spray-Dried Composite Particles of Lactose and Sodium Alginate.
- Spray-Dried Lactose Composite Particles Containing an Ion Complex of Alginate-Chitosan for Designing a Dry-Coated Tablet Having a Time-Controlled Releasing Function.
- Temperature- and Moisture-Induced Crystallization of Amorphous Lactose in Composite Particles with Sodium Alginate Prepared by Spray-Drying.
- In vitro inhalation behavior of spherically agglomerated steroid particles with carrier lactose
- Physical Stability of Size Controlled Small Unilamellar Liposomes Coated with a Modified Polyvinyl Alcohol.
- Properties of a Peptide Containing DL-Lactide/glycolide Copolymer Nanospheres Prepared by Novel Emulsion Solvent Diffusion Methods.
- Optimum Heat Treatment Conditions for Masking the Bitterness of the Clarithromycin Wax Matrix
- Determination of Optimum Processing Temperature for Transformation of Glyceryt Monostearate
- Preparation of a Directly Tabletable Controlled-Release Matrix Filler with Microcrystalline Cellulose Modified with Hydroxypropylmethylcellulose.
- Preparation of prolonged-release matrix tablet of acetaminophen with pulverized low-substituted hydroxypropylcellulose via wet granulation.
- Preparation of a Sustained-Release Matrix Tablet of Acetaminophen with Pulverized Low-Substituted Hydroxypropylcellulose via Dry Granulation.
- The effects of particle size, degree of hydroxypropoxyl substitution and moisture content of low-substituted hydroxypropylcellulose on the compactibility of acetaminophen and the drug release rate of the resultant tablets.
- Preparation of Controlled releasing Acrylic Polymer Microspheres of Acebutolol Hydrochloride and Those Powder Coated Microspheres with Sodium Alginate in a Polymeric Spherical Crystallization System.
- Improved Static Compression Behaviors and Tablettabilities of Spherically Agglomerated Crystals Produced by the Spherical Crystallization Technique with a Two-Solvent System.
- Parameters determining the agglomeration behaviour and the micromeritic properties of spherically agglomerated crystals prepared by the spherical crystallization technique with miscible solvent systems.
- Preparation of Controlled Releasing Acrylic Polymer Microspheres of Acebutolol Hydrochloride and Those Powder Coated Microspheres with Sodium Alginate in a Polymeric Spherical Crystallization System
- Improvements in flowability and compressibility of pharmaceutical crystals for direct tabletting by spherical crystallization with a two-solvent system.
- Agglomeration Behaviour and Modification of Spherical Crystallization Process of Pharmaceuticals by the Emulsion-Solvent-Diffusion Method and Proposed Closed-Circuit Batch System.
- Improvement in Compressing Properties of Drug crystals Using a Spray-drying Technique.
- Aqueous colloidal polymer dispersions of biodegradable DL-lactide/glycolide copolymer as basis for latex films : a new approach for the development of biodegradable depot systems.
- Hydrogen retention properties of SiC/SiC composites as plasma facing material of fusion reactor (第51回真空に関する連合講演会プロシーディングス)
- Penetration of Outer Layered Particles of Agglomerate into Inner Intersticies of Agglomerate during Spherical Agglomeration in Liquid.
- Core-particle Design and Control of Coating Film by Suspension Coating with Chitosan.
- Penetration of Outer Layered Particles of Agglomerate into Inner Intersticies of Agglomerate during Spherical Agglomeration in Liquid
- Enteral Absorption of Insulin in Rats from Mucoadhesive Chitosan-Coated Liposomes.
- The Design of Inhalation Dry Powders by the Surface Modification of Drug Particles.
- Tabletting properties of bucillamine agglomerates prepared by the spherical crystallization technique.
- Stabilization of Lactide/Glycolide Copolymer(PLGA) Nanospheres with Peptide-drug by Freeze-drying.
- Aerosolization of Lactide/Glycolide Copolymer(PLGA)Nanospheres for Pulmonary Delivery of Peptide-drugs.
- The Analysis of Drug Release from Diluted Water/oil/water Emusions by a Model of the Rupture of Oil Membrane.
- Preparation of Agglomerated Crystals for Direct Tabletting and Microencapsulation by the Spherical Crystallization Technique with a Continuous System.
- In Vitro Drug Release Behavior of D, L-Lactide/Glycolide Copolymer (PLGA) Nanospheres with Nafarelin Acetate Prepared by a Novel Spontaneous Emulsification Solvent Diffusion Method.