Identification and Biological Activity of Microbial Metabolites of Xanthohumol
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概要
- 論文の詳細を見る
Microbial transformation of xanthohumol using the culture broth of Cunninghamella echinulata NRRL 3655 afforded (2S)-8-[4"-hydroxy-3"-methyl-(2"-Z)-butenyl]-4',7-dihydroxy-5-methoxyflavanone (5) and (2S)-8-[5"-hydroxy-3"-methyl-(2"-E)-butenyl]-4',7-dihydroxy-5-methoxyflavanone (6). Xanthohumol (1) and flavanone 6 as well as (E)-2"-(2'"-hydroxyisopropyl)-dihydrofurano[2",3":4',3']-2',4-dihydroxy-6'-methoxychalcone (2), (2S)-2"-(2'"-hydroxyisopropyl)-dihydrofurano[2",3":7,8]-4'-hydroxy-5-methoxyflavanone (3) obtained with Pichia membranifaciens showed antimalarial activity against Plasmodium falciparum.
- 公益社団法人日本薬学会の論文
- 2003-11-01
著者
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Ferreira Daneel
National Center For Natural Products Research The University Of Mississippi:department Of Pharmacogn
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Khan Ikhlas
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, Univer
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Khan I
National Center For Natural Products Research The University Of Mississippi:department Of Pharmacogn
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Herath Wimal
National Center For Natural Products Res. The Univ. Of Mississippi
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Khan Ikhlas
National Cente For Natural Products Research Research Institute Of Pharmaceutical Sciences:departmen
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KHAN Shabana
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The Un
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Khan S
Univ. Mississippi Ms Usa
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Khan Shabana
National Center For Natural Products Research Research Institute Of Pharmaceutical Sciences School O
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