Reaction of Phosgene with the Tricycle Related to the Minor Base of Phenylalanine Transfer Ribonucleic Acids
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概要
- 論文の詳細を見る
1-Benzylwye (8) underwent electrophilic substitution at the 7-position in the presence of phosgene and pyridine in tetrahydrofuran (THF) to afford the 1,4-dihydropyridines (11, 10, and 14) together with the carboxylic acid 6 and its methyl ester 2 after short treatment of the reaction mixture with methanol and then with water. When triethylamine was used instead of pyridine, phosgene reacted with triethylamine rather than 8, producing (E)-3-(diethylamino)propenoyl chloride (17) and diethylcarbamoyl chloride (18).
- 公益社団法人日本薬学会の論文
- 2002-12-01
著者
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ITAYA Taisuke
Faculty of Pharmaceutical Sciences, Kanazawa University
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KANAI Tae
Faculty of Pharmaceutical Sciences, Kanazawa University
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Kanai Tae
Faculty Of Pharmaceutical Sciences Kanazawa University
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Itaya Taisuke
Faculty Of Pharmaceutical Sciences Kanazawa University
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