MRP5b/SMRP mRNA is Highly Expressed in Metallothionein-Deficient Mouse Liver

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概要

• 論文の詳細を見る

• To investigate whether multidrug resistance protein 5 (MRP5) functions as a xenobiotic detoxification factor, we measured MRP mRNA expression levels in metallothionein (MT)-I, II knockout mouse, and the results showed that MRP5b/SMRP, a splicing variant of MRP5, was highly expressed in the liver of MT-I, -II null mice.

• 公益社団法人日本薬学会の論文
• 2003-12-01

著者

• Nishio Kazuto

  明治薬科大学 分析化学

• SUZUKI Toshihiro

  Department of Materials Technology, Faculty of Engineering, Chiba University

• TOGAWA Tadayasu

  Departments of Analytical Biochemistry, Meiji Pharmaceutical University

• TANABE Shinzo

  Departments of Analytical Biochemistry, Meiji Pharmaceutical University

• Naganuma A

  Laboratory Of Molecular And Biochemical Toxicology Graduate School Of Pharmaceutical Science Tohoku

• Tanabe S

  Departments Of Analytical Biochemistry Meiji Pharmaceutical University

• Tanabe S

  Meiji Coll. Pharmacy Tanashi Jpn

• Tanabe Shinzo

  Department Of Analytical Biochemistry Meiji Pharmaceutical University

• Suzuki T

  Departments Of Analytical Biochemistry Meiji Pharmaceutical University

• Togawa T

  Departments Of Analytical Biochemistry Meiji Pharmaceutical University

• Togawa Tadayasu

  Department Of Analytical Biochemistry Meiji Pharmaceutical University

• Suzuki T

  Department Of Xenobiotic Metabolism And Molecular Toxicology Institute Of Pharmaceutical Sciences Hi

• Agui Mika

  Department of Analytical Biochemistry, Meiji Pharmaceutical University

• Nganuma Akira

  Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Science, Tohok

• Nishio Kazuto

  Project Ward, National Cancer Center Hospital

• Tsujino Seiichi

  Department Of Peripheral Nervous System Research National Institute Of Neuroscience Ncnp

• Agui Mika

  Department Of Analytical Biochemistry Meiji Pharmaceutical University

• Suzuki Toshihiro

  Department Of Analytical Biochemistry Meiji Pharmaceutical University

• Nishio Kazuto

  Project Team For Pharmacogenetics National Institute Of Health Sciences

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