Characterization of Ascidian Plasma Growth Factors Promoting the Proliferation of Mouse Thymocytes
スポンサーリンク
概要
- 論文の詳細を見る
The plasma of a solitaly ascidian, Halocynthia roretzi, stimulates the proliferation of mouse thymocytes in the presence of a mitogen, phytohemagglutinin P (PHA-P). Eight factors capable of stimulating the proliferation of mouse thymocytes were isolated from H. roretzi plasma by procedures including hydrophobic chromatography, gel filtration, and anion-exchange chromatography. Four active fractions with molecular weights of 100-110 K, 75-90 K, and 5-6 K were first separated by gel filtration. Each of these fractions was then separated into two fractions with different ionic properties by anion-exchange chromatography. The eight factos thus obtained have different heat stabilities, heparin-binding abilities, and PHA-P sensitivities.
- 社団法人日本動物学会の論文
著者
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YOKOSAWA Hideyoshi
Department of Biochemistry, Faculty of Pharmacological Science, Hokkaido University
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Azumi Kaoru
Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University
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Iizuka Junko
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Hokkaido University
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Yokosawa Hideyoshi
Department Of Biochemistry Graduate School Of Pharmaceutical Sciences Hokkaido University
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Azumi Kaoru
Hokkaido Univ. Sapporo Jpn
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Azumi Kaoru
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Hokkaido University
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Yokosawa Hideyoshi
Department Of Biochemistry Faculty Of Pharmaceutical Sciences Hokkaido University
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