Effect of Hypothalamic Extract on the Prolactin Release from the Bullfrog Pituitary Gland with Special Reference to Thyrotropin-Releasing Hormone (TRH) : Endocrinology
スポンサーリンク
概要
- 論文の詳細を見る
Acid extract of bullfrog hypothalami but not of rat hypothalami stimulated the release of prolactin (PRL) from the bullfrog pituitary gland in vitro. Since frog hypothalamus is known to contain thyrotropin-releasing hormone (TRH), a stimulator of PRL release, much more than rat hypothalamus, experiments were performed to determine whether PRL-releasing activity of the frog hypothalamic extract is derived from TRH it contains. PRL-releasing activity in the hypothalamic extract was nullified by incubation with bullfrog plasma. When the extract was fractionated on Sephadex G-25 chromatography, significant PRL-releasing activity was found in the fraction which is presumed to contain TRH. The activity of the hypothalamic extract was markedly reduced by co-incubation with IgG fraction separated from antiserum to TRH. These results indicate that TRH is one of the major PRL-releasing factors in the hypothalamic extract.
- 社団法人日本動物学会の論文
- 1988-04-15
著者
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KIKUYAMA Sakae
Department of Biology, School of Education, Waseda University
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Kikuyama Sakae
Department Of Biology Faculty Of Science Shizuoka University
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Suzuki Masakazu
Dep. Of Biology Fac. Of Sci. Shizuoka Univ.
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SEKI Tatsunori
Department of Anatomy, Juntendo University School of Medicine
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Seki Tatsunori
Department Of Anatomy Juntendo University Of Medicine
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Kikuyama S
Waseda Univ. Tokyo Jpn
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SUZUKI MITSUO
Department of Physiology, Institute of Endocrinology, Gunma University
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Suzuki Mitsuo
Department Of Obstetrics And Gynecology Showa University School Of Medicine
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Suzuki M
Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni
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Suzuki Mitsuo
Department Of Biology College Of Liberal Arts Kanazawa University
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