Co-expression of NGF and Its High-affinity Receptor TrkA in the Rat Carotid Body Chief Cells
スポンサーリンク
概要
- 論文の詳細を見る
The expression and localization of NGF and its high-affinity receptor, TrkA, in the rat carotid body was investigated by use of in situ hybridization and immunohistochemistry, respectively. The immunoreactivity for TrkA was detected in most of chief cells and sustentacular cells, as well as in some nerve axons and perineurial cells, but not in Schwann cells. In electron microscopy, the immunoreactivity was localized to the cytoplasm. The mRNA for NGF was localized to most of chief cells and possibly also to sustentacular cells. These results demonstrated that carotid body chief cells, having the neural crest origin, produce both NGF and TrkA, implying a paracrine-autocrine role of NGF in the carotid body.
- 日本組織細胞化学会の論文
著者
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Iseki Shoichi
Kanazawa Univ. Kanazawa Jpn
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Iseki Shoichi
Department Of Histology And Embryology Graduate School Of Medical Science Kanazawa University
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YAMAMOTO Miyuki
Department of Geriatric Medicine, Ehime University Graduate School of Medicine
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Yamamoto Miyuki
Department Of Histology And Embryology Graduate School Of Medical Science Kanazawa University
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Yamamoto Miyuki
Department Of Applied Chemistry Division Of Bioengineering Muroran Institute Of Technology
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Yamamoto M
Department Of Histology And Embryology Graduate School Of Medical Science Kanazawa University
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Iseki Shoich
Department of Histology and Embryology, Graduate School of Medical Science, Kanazawa University
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井関 尚一
Department of Anatomy, School of Medicine, Kanazawa Univeristy
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山本 美由紀
Department of Histology and Embryology, Graduate School of Medical Science, Kanazawa University
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