Tissue Plasminogen Activatorの組織化学的研究 : 膀胱におけるtissue plasminogen activatorとalkaline phosphatase

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The functional significances of the bladder epithelium are not yet well known. The transitional epithelium of the bladder is subjected to considerable physiological stimuli such as pressure changes during filling and emptying of the bladder and variations in the osmotic concentration of urine. The transitional epithelium of the bladder is well adapted to these stresses. It is generally known that the special histological structure and interrelationship of component cells of the transitional epithelium and the presence of a condensation of cytoplasm in surface cells are accepted generally. The mechanism by which the bladder epithelium is adapted to changes in the area of the mucous membrane during filling and emptying is also known. It has long been known experimentally and clinically that vesical mucoa regenerate rapidly even after its complete excision.20) The existence of the basal membrane in the bladder mucosa was demonstrated by many authors.13)14)35)41) Another open problems are that of active-transport function of the transitional epithellum.3)17)21)22)23)42)44)45)46)47)48)
社団法人日本泌尿器科学会の論文