連鎖球菌による実験的根尖病巣に対する各種根管充填剤の効果に関する研究

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Experimental apical infections were established in the teeth of dogs inoculated with known amount of a strain of Streptococcus viridans that was isolated from apical infected lesion of human teeth. The infected root canals were filled with the commercial filling materials such as AH 26, N_2 and Canals, and the effects were examined radiologically and pathohistologically. The findings were summarized as follows. 1. The cell suspension of Streptococcus viridans in the amount of 0.02 ml containing 4×10^3 of cells inoculated to the teeth of dogs produced an acute inflammation in the tissues about the root tip by approximately 3 weeks. 2. When the Penicillin paper point of 10 units was applied to the infected root, the acute exudative inflammation in the root tip was subsided in the course of about 1 week and granular tissue started to proliferate. The lesion eventually became localized and showed the picture of chronic lesion. 3. When each of the above filling materials was applied to the chronic lesion and the effect compared with that of non-treated controls, distinct improvement was observed in the healing process of the treated cases. 4. In non-treated cases, there remained more or less an extensive region of chronic inflammation even 9 weeks after treatment, while in the treated cases there remained only traces of inflammatory foci that were localized in the root tip region. 5. Comparison of relative merit of these 3 canal filling materials in the healing of apical lesion showed that AH26 was most excellent, followed by N_2 and Canals. 6. In order to achieve the best use of these filling materials, it is advised to fill the root canal completely and not to leave any space unfilled within the canal.
九州歯科学会の論文
1973-03-31

連鎖球菌による実験的根尖病巣に対する各種根管充填剤の効果に関する研究

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