Effects of Dual-Chamber Pacing on Regional Myocardial Deformation in Patients With Hypertrophic Obstructive Cardiomyopathy
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概要
- 論文の詳細を見る
Background This study examined the effects of dual-chamber pacing (DDD) on regional myocardial deformation, as determined by echocardiographic strain and strain rate (SR) imaging, in patients with hypertrophic obstructive cardiomyopathy (HOCM). Methods and Results Fourteen patients (11 men, 3 women; mean age 55±16 years) who had been on long-term DDD (mean period 7.4±2.1 years) underwent strain and SR imaging. Before and after DDD, the peak strain (%) and SR (s^<-1>) during systole were assessed in 8 segments in 4 left ventricular (LV) walls. With DDD turned on, peak strain and SR were significantly increased in the basal anteroseptal (strain -10.2±6.8 to -1.0±6.4, p<0.005; SR -0.76±0.46 to 0.05±0.58, p<0.001) and septal segments (strain -11.2±8.9 to -2.2±7.7, p<0.005; SR -0.85±0.54 to -0.19±0.75, p<0.05), but not in the basal posterior (strain -15.0±13.0 to -13.4±9.2, p=NS; SR -1.37±0.57 to -1.93±0.65, p=NS) and lateral segments (strain -18.1±10.2 to -15.7±5.6, p=NS; SR -1.33±0.68 to -0.84±0.88, p=NS). These findings were associated with a modest, but significant, change in the LV pressure gradient (24±12 mmHg to 14±7 mmHg, p<0.001). Conclusions In patients with HOCM, DDD appeared to produce myocardial lengthening in the basal septum during systole, which may have implications for the mechanism of reducing LV outflow obstruction during DDD.
- 社団法人日本循環器学会の論文
- 2005-12-20
著者
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Suwa M
Hokusetsu General Hospital
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Kitaura Yasushi
Third Department of Internal Medicine, Osaka Medical College
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ITO Takahide
Third Department of Internal Medicine, Osaka Medical College
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Suwa Michihiro
Third Department of Medicine, Osaka Medical College
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Hozumi Tomomi
Third Division, Department of Internal Medicine, Osaka Medical College
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Sakai Yasuhiko
Third Division, Department of Internal Medicine, Osaka Medical College
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Ito Takahide
Hayama Heart Center
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Sakai Yasuhiko
Third Division Department Of Internal Medicine Osaka Medical College
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Suwa Michihiro
Dept. Of Intern. Med. Osaka Medical Colledge.
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Suwa Michihiro
3rd Division Department Of Internal Medicine Osaka Medical College
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Suwa Michihiro
Third Department Of Internal Medicine Osaka Medical College
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Kitaura Yasushi
Third Department Of Internal Medicine Osaka Medical College
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Hozumi Tomomi
Third Division Department Of Internal Medicine Osaka Medical College
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Suwa Michihiro
Iii Div Osaka Med. College
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Ito Takahide
Third Department Of Internal Medicine Osaka Medical College
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Sakai Yasuhiko
The Third Division Department Of Internal Medicine Osaka Medical College
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Suwa Michihiro
大阪医科大学
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Ito Takahide
Third Department Of Medicine Osaka Medical College
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Suwa Michihiro
3rd Div. Dept. Intern. Med. Osaka Medical College
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