自己組織化単分子膜修飾電極を用いるドーパミンの選択的定量と共存タンパクの影響

概要

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A self-assembled monolayer consisting of 3,3'-thiodipropionic acid and n-decyl mercaptan formed on a gold electrode was studied for a sensitive and selective determination of dopamine. The experimental results show that the monolayer exhibits both excellent sensitivity and stability, even in the presence of ascorbic acid and protein. A detection limit of 5.0×10^<-6> M for dopamine was obtained in flow injection analysis by the optimizing experimental conditions, such as the solution pH, flow velocity of the carrier solution and the electrode potential. The current response of the modified electrode showed excellent stability in the presence of 0.2% albumin. Even with ascorbic acid in 10-fold excess, dopamine could be detected within an error of about 3%.
社団法人日本分析化学会の論文
2004-11-05