アナフィラキシーショックとビタミンB_2代謝に関する研究 : (V)血清過敏症のさいのビタミンB_2代謝

概要

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The riboflavin concentration in the blood of two pharyngeal diphtheria patients with serum disease was examined. In the first case, a wide serum eruption appeared on the knee on the 7th day after the injection of serum. On 5th and 10th day, free and ester forms of riboflavin decreased, especially it was remarkable in case of ester form. In the second case, a slight serum eruption appeared on 5th day after the serum injection. On the same day, a slight increase of the amount of free riboflavin and decrease of that of the ester form were observed. On the 10th day the total riboflavin level was restored to original. The level of ester form, however, was still lower than the original. The results mentioned above suggest that the phosphorylating ability of riboflavin is inhibited when the serum eruption occurs.
日本ビタミン学会の論文