アナフィラキシーショックとビタミンB_2代謝に関する研究 : (II)アナフィラキシーショックの臓器ビタミンB_2濃度および尿中ビタミンB_2排泄におよぼす影響

概要

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As in the previous report, an anaphylactic shock was caused on guinea pigs by injecting horse serum. The anaphylactic shock was followed by the decrease of riboflavin concentration. The most remarkable decrease was observed in the liver. After 10-20 minutes, the total riboflavin concentration was about 3200-3250 μg% (normal 4780 μg%). The ester ratio decreased gradually after the anaphylactic shock occurred. After 90 minutes, about 23% of the vitamin decreased in the liver. Fourty-one percent decreased in the adrenal glands after 60 minutes. The amount of riboflavin, especially of free form, excreted in the urine during the next 12 hours was slightly higher than that of the control. When the shock occurred, the availability of the vitamin was decreased. It was supposed that a large amount of riboflavin might be transferred to gall bladder than that excreted in the urine.
日本ビタミン学会の論文