アナフィラキシーシッョクとビタミンB_2代謝に関する研究 : (IV)アナフィラキシーショック誘発後の諸臓器ビタミンB_2濃度の消長のビタミンB_2分別定量法による検討

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The riboflavin concentration in blood and in various organs of a guinea pig decreased by the injection which caused an anaphylactic shock. A chromatographical investigation was carried out on the amounts of the riboflavin relating substances in each tissue. In the blood, FAD and FMN decreased 20 minutes after the injection, and 60 minutes after, both increased a little. However, free riboflavin increased from 1.9 μg% to 2.2 μg% and 2.5 μg%, during the same time. In the liver, 20 minutes after the injection, FAD decreased remarkably (about 1400 μg%), while FMN (about 340 μg%) and free riboflavin (about 190 μg%) increased. In the kidneys, 20 minutes after the injection, FAD decreased remarkably (about 1000 μg%), while FMN (about 250 μg%) and free vitamin (about 400 μg%) increased. In the suprarenal capsule, 60 minutes after the injection, the remarkable decrease of FAD (about 1000 μg%) and the conspicuous increase of free vitamin (about 450 μg%) were observed. In the lungs, 20 minutes after the injection the decrease of FAD (about 350 μg%) was observed.
日本ビタミン学会の論文