アノイリナーゼ菌(K・A)の代謝に関する研究 : (VIII)グルタミン酸代謝に及ぼす糖類の影響(1)

概要

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It is known that Bacillus aneurinolyticus has no ability to form acids in the aerobic conditions from sacchrides with the exception of glycerine. Then, the effects of glucose and glycerine on the aerobic metabolism of glutamate were examined. By adding glycerine to the medium, the glutamate and pyrrolidone carboxylate metabolisms were remarkably reduced, and "Crabtree effect" appeared strongly. A similar result was obtaind in the α-ketoglutarate metabolism. On the contrary, an addition of glucose hardly influenced on the respiratory metabolisms of glutamate and α-ketoglutarate, but those of pyrrolidone carboxylate and succinate were hastened remarkably. These phenomena suggest that there is a relation between the synthesis of saccharide and the metabolism of pyrrolidone carboxylate.
日本ビタミン学会の論文