In Normoglycemic Koreans, Insulin Resistance and Adipocity are Independently Correlated With High Blood Pressure
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概要
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Background There is some controversy about the role of insulin resistance (IR) in the regulation of blood pressure (BP). Moreover, a large study of the association between BP and IR has not been conducted in normal glucose tolerance Asians. The present study investigated the relationships between IR, body mass index (BMI) and waist circumference and BP in normoglycemic Koreans. Methods and Results Anthropometric indices of adiposity, metabolic variables (fasting serum insulin and a homeostasis model assessment (HOMA) index of insulin sensitivity), BP and several cardiovascular risk factors were measured during a cross-sectional survey of 49,076 normoglycemic Korean subjects. A high BP was defined as a systolic BP ≥ 140mmHg or a diastolic BP ≥ 90mmHg. The prevalence of high BP by HOMA grading was 0.985 (95% confidence interval (CI) 0.857-1.132, p=0.835), 1.180 (95% CI 1.032-1.350, p=0.016), 1.289 (95% CI 1.129-1.472, p<0.001), and 1.540 (95% CI 1.341-1.768, p<0.001) times higher in subjects in the second, third, fourth, and fifth quintiles, respectively, compared with those in the first quintile. In addition, age, sex, waist circumference and BMI were found to be significantly associated with a high BP. Conclusion IR, BMI and waist circumference are independently correlated with high BP in normoglycemic Koreans. (Circ J 2004; 68: 898-902)
- 社団法人日本循環器学会の論文
- 2004-09-20
著者
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Kim Bum
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Kim Sun
Division Of Information And Electronics Korea Institute Of Science And Technology
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Park Jung
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Kim Byung
Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan Univ
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Sung Ki
Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan Univ
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Kim Bum
Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan Univ
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Kang Jin
Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan Univ
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Lee Man
Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan Univ
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Park Jung
Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan Univ
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Rhee Eun
Divisions of Endocrinology, Department of Internal Medicine, Sungkyunkwan University, School of Medi
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Lee Won
Divisions of Endocrinology, Department of Internal Medicine, Sungkyunkwan University, School of Medi
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Kim Hyang
Divisions of Nephrology, Department of Internal Medicine, Sungkyunkwan University, School of Medicin
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Lee Kyu
Divisions of Nephrology, Department of Internal Medicine, Sungkyunkwan University, School of Medicin
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Ryu Seung
Divisions of Occupational medicine, Department of Internal Medicine, Sungkyunkwan University, School
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Kirn Se
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Lee Man
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Kim Byung
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Ryu Seung
Departments Of Occupational Medicine Kangbuk Samsung Hospital Sungkyunkwan University School Of Medi
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Rhee Eun
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Kim Hyang
Department Of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School Of Medicine
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Kang Jin
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Sung Ki
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Lee Won
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Kim Sun
Department Of Internal Medicine Institute Of Medical Research Sungkyunkwan University School Of Medi
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Lee Won
Division Of Applied Plant Sciences Kangwon National University
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Lee Kyu
Divisions Of Nephrology Department Of Internal Medicine Sungkyunkwan University School Of Medicine K
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Kim Byung
Division Of Breast And Endocrine Surgery Hallym University Sacred Heart Hospital College Of Medicine
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Lee Kyu
Division Of Environmental And Biological Engineering Kangwon National University
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Kim Sun
Division Of Endocrinology And Metabolism Department Of Medicine Samsung Medical Center Sungkyunkwan University School Of Medicine
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Kang Jin
Division Of Cardiology Department Of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School Of Medicine
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Kim Byung
Division Of Cardiology Department Of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School Of Medicine
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Park Jung
Division of Advanced Electrics and Optical Science, Department of Systems Innovation, Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan
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RHEE Eun
Division of Endocrinology and Metabolism Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine
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