Efficient Synthesis of a Sialyl T-antigen-linked Glycopeptide by the Chemoenzymatic Method
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概要
- 論文の詳細を見る
A sialyl T-antigen-linked tetrapeptide was prepared by the combined method of chemical synthesis and enzymatic synthesis. The GalNAc-linked peptide was first obtained by using a commercial peptide synthesizer, and then a galactose residue was attached with β-(1→3)-linkage by transglycosylating with a recombinant β-galactosidase from Bacillus circulans. The sialic acid residue was then combined by α-(2→3)-linkage with sialytransferase from rat liver.
- 社団法人日本農芸化学会の論文
- 2000-08-23
著者
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Ajisaka Katsumi
Meiji Dairies Co.
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Miyasato M
Meiji Dairies Co. Kanagawa Jpn
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MIYASATO Mariko
Meiji Institute of Health Science, Meiji Milk Products Co. Ltd.
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Ajisaka Katsumi
Meiji Institute of Health Science, Meiji Milk Products Co. Ltd.
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