Pericytes from Microvessel Fragment Produce Type IV Collagen and Multiple Laminin Isoforms
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概要
- 論文の詳細を見る
In the microvascular system, pericytes are located at the abdominal side of capillary endothelial cells. To discover the role of pericytes in the microvascular system, we have analyzed the extracellular proteins secreted from pericytes isolated from microvessel fragments of rat epididymal fat pads and found that they synthesize substantial amounts of basement membrane components such as type IV collagen and laminins. Secretion of type IV collagen was markedly stimulated by ascorbic acid phosphate. Reducing and non-reducing sodium dodecyl sulfate gel electrophoresis showed that pericytes produce six laminin chains assembled into different trimeric isoforms. Two of them were similar to laminin variants produced by aortic and pulmonal endothelial cells but others were suggested to be novel variants.
- 社団法人日本農芸化学会の論文
- 1996-05-23
著者
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Jeon Hoon
Graduate Program Of Biochemical Regulation School Of Agricultural Sciences Nagoya University
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Jeon Hoon
名古屋大学 大学院
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Kitagawa Y
名古屋大学 生命農学研究科
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Kitagawa Y
Nagoya Univ. Nagoya Jpn
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Kitagawa Yasuo
Graduate School Of Bioscience Fukui Prefectural University
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Ono Masaaki
Graduate Program Of Biochemical Regulation School Of Agricultural Sciences Nagoya University
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KUMAGAI Chino
Graduate Program of Biochemical Regulation, School of Agricultural Sciences, Nagoya University
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MIKI Kiyoshi
Graduate Program of Biochemical Regulation, School of Agricultural Sciences, Nagoya University
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MORITA Akihito
Nagoya University BioScience Center
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Kitagawa Yasuo
Graduate Program For Biochemical Regulation Graduate School Of Agricultural Sciences
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Kitagawa Yasuo
Graduate Program Of Biochemical Regulation School Of Agriculture Nagoya University And Nagoya Univer
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Kumagai Chino
Graduate Program Of Biochemical Regulation School Of Agricultural Sciences Nagoya University
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Miki K
Graduate Program For Biochemical Regulation Graduate School Of Agricultural Sciences
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Miki Kiyoshi
Graduate Program for Biochemical Regulation, Graduate School of Agricultural Sciences
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