Proteasome inhibitors and Na channel blocker increase the KV1.5 channel activities by modification of the intracellular trafficking
スポンサーリンク
概要
- 論文の詳細を見る
- 社団法人日本循環器学会の論文
- 2002-03-31
著者
-
Shigemasa Chiaki
Department of Cardiovascular Medicine, Faculty of Medicine, Tottori University
-
Hisatome Ichiro
Division of Regenerative Medicine and Therapeutics, Tottori University Faculty of Medicine
-
Shigemasa Chiaki
Division Of Regenerative Medicine And Therapeutics Department Of Genetic Medicine And Regenerative M
-
Miake Junichiro
Division of Immunology, Molecular and Cellular Biology, School of Life Sciences, Tottori University
-
Kato Masaru
Division of Molecular Medicine and Therapeutics, Tottori University
-
Igawa Osamu
Division of Molecular Medicine and Therapeutics, Tottori University
-
Murata Mitsunobu
Division of Cardiovascular Medicine
-
Murata Mitsunobu
Department Of Cardiovascula Medicine Jichi-medical University
-
Hisatome Ichiro
Division Of Molecular Medicine And Therapeutics Department Of Multidisciplinary Internal Medicine To
-
SASAKI Norihito
Division of Regenerative Medicine and Therapeutics, Department of Genetic Function and Regenerative
-
Yatsuhashi Toru
Division of Cardiology, Department of Medicine, Faculty of Medicine, Tottori University
-
Ninomiya Haruaki
鳥取大学 遺伝子再生医療学
-
Ninomiya H
Department Of Neurobiology Faculty Of Medicine Tottori University
-
Ninomiya Haruaki
Department Of Biological Regulation Tottori University Faculty Of Medicine
-
Ninomiya Haruaki
鳥取大学医学部附属脳幹性疾患研究施設 脳神経小児科部門
-
Sasaki Norihito
Division Of Regenerative Medicine And Therapeutics Institute Of Regenerative Medicine And Biofunctio
-
Tanaka Yasushi
Department Of Cardiovascular Medicine Tottori University Hospital
-
Ohtahara Akira
Division of Cardiology, San-in Rousai Hospital
-
Kato Masahiko
Department Of Cardiovascular Medicine Faculty Of Medicine Tottori University
-
Ohtahara Akira
Division Of Cardiology San-in Rousai Hospital
-
Ninomiya Haruaki
Division of Neurobiology, Department of Biomedical Sciences, Tottori University
-
Kato Masaru
Division Of Cardiology Cardiovascular Center Tsuchiura Kyodo Hospital
-
Ohtahara Akira
Department Of Cardiology San-in Rosai Hosipital
-
Ninomiya Haruaki
Department Of Neurobiology School Of Life Sciences Faculty Of Medicine Tottori University
-
Miake Junichiro
Division Of Immunology Molecular And Cellular Biology School Of Life Sciences Tottori University
-
MIAKE Junichiro
Division of Cardiology, Tottori University Hospital
-
Miake Junichiro
Division of Cardiology, Tottori University Faculty of Medicine
-
Igawa Osamu
Division of Cardiovascular Medicine, Department of Internal Medicine, Tottori University Faculty of Medicine
-
Shigemasa Chiaki
Division of Cardiovascular Medicine, Department of Internal Medicine, Tottori University Faculty of Medicine
-
Hisatome Ichiro
Division of Cardiovascular Medicine, Department of Internal Medicine, Tottori University Faculty of Medicine
関連論文
- PE-404 Improvement of γ-glutamyl Transferase Activity by CPAP may Reduce Cardiovascular Risk in Patients with Obstructive Sleep Apnea(PE068,Obesity/SAS 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
- Addition of Losartan to Angiotensin-Converting Enzyme Inhibitors Improves Insulin Resistance in Patients With Chronic Heart Failure Treated Without β-Blockers
- A Simple Risk Score to Predict In-Hospital Death of Elderly Patients With Acute Decompensated Heart Failure : Hypoalbuminemia as an Additional Prognostic Factor
- PJ-584 Contributing Factors for the Incidence of Paroxysmal Atrial Fibrillation in Patients with Obstructive Sleep Apnea(PJ098,Obesity/SAS (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-513 Hyponatremia is an Important Predictor for In-hospital Mortality in Heart Failure Patients with Preserved Ejection Fraction(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulati
- Usefulness of three-dimensional echocardiography in assessing right ventricular function in patients with primary pulmonary hypertension
- PJ-513 Hyponatremia is an Important Predictor for In-hospital Mortality in Heart Failure Patients with Preserved Ejection Fraction(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulati
- OE-081 A Simple Risk Score to Stratify Risk of In-hospital Mortality in Elderly Patients with Acute Decompensated Heart Failure(OE14,Heart Failure (Biomarker) (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation S
- PJ-113 Nkx2.5(+) But Not Flk1(+) Cardiac Progenitor Cells are Fated to Pacemaker Cells Expressing I_f Predominantly Encoded by HCN4 Gene(Heart failure, basic(05)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation So
- PJ-781 Continuous Positive Airway Pressure Therapy Reduces Serum Amyloid A/LDL Complex in Patients with Obstructive Sleep Apnea(Diabetes/Obesity/Metabolic syndrome-13, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-104 Delayed Onset of Beating and Decreased Expression of T-type Ca^ Channel in Mouse ES Cell-Derived Cardiocytes Carrying Human Chromosome 21(Excitation-contraction coupling/Ion channel, The 71st Annual Scientific Meeting of the Japanese Circulatio
- PE-526 Nasal Continuous Positive Airway Pressure and Serum Uric Acid Levels in Patients with Obstructive Sleep Apnea(Kidney/Renal circulation-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Inhibition of Inward Rectifier K^+ Currents by Angiotensin II in Rat Atrial Myocytes : Lack of Effects in Cells from Spontaneously Hypertensive Rats
- Effects of Angiotensin II on the Action Potential Durations of Atrial Myocytes in Hypertensive Rats
- Developmental Changes of Ni^ Sensitivity and Automaticity in Nkx2.5-Positive Cardiac Precursor Cells From Murine Embryonic Stem Cell
- State-Dependent Blocking Actions of Azimilide Dihydrochloride (NE-10064) on Human Cardiac Na^+ Channels
- L-Cysteine Prevents Oxidation-Induced Block of the Cardiac Na^+ Channel Via Interaction With Heart-Specific Cysteinyl Residues in the P-Loop Region
- PJ-513 Hyponatremia is an Important Predictor for In-hospital Mortality in Heart Failure Patients with Preserved Ejection Fraction(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulati
- PJ-456 Role of Cysteinyl Leukotrienes in the Progression of Atherosclerosis in Mouse and in Human(PJ077,Infection/Inflammation/Immunity (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-280 The Essential Anatomical Information of the Left Ventricular Outflow Tract for Catheter Ablation : Anatomical Investigation in 100 Autopsied Hearts(PJ047,Arrhythmia, Others (Clinical/Pathophysiology) 3 (A),Poster Session (Japanese),The 73rd Annual
- PJ-276 Unusual Veins Draining into the Left Atrial Chamber : Anatomical Investigation in 100 Autopsied Hearts(PJ047,Arrhythmia, Others (Clinical/Pathophysiology) 3 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulatio
- PE-480 The Paradoxical Prolongation of Stimulation-A Interval during Para-hisian Pacing for Diagnosis of the Acessory Pathway(PE081,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 4 (A),Poster Session (English),The 73rd Annual Scientific Meeting of the
- PE-352 Spironolacton, not Fursemide, Improved Insulin Resistance in Patients with Chronic Heart Failure(PE059,Heart Failure (Treatment) 2 (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PE-007 The Essential Anatomical Information for Catheter Ablation around the Base of the Pulmonary Trunk : anatomical Investigation in 100 Autopsied Hearts(PE002,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 1 (A),Poster Session (English),The 73rd Ann
- OE-328 The Useful Anatomical Information for Catheter Ablation Concerning the Relationship between the Aortic Non-coronary Cusp and the His Bundle(OE56,Arrhythmia, Others (Clinical/Pathophysiology) (A),Oral Presentation (English),The 73rd Annual Scientifi
- OE-081 A Simple Risk Score to Stratify Risk of In-hospital Mortality in Elderly Patients with Acute Decompensated Heart Failure(OE14,Heart Failure (Biomarker) (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation S
- FRS-091 Impairment of Ubiquitin-Proteasome System Caused by a Missense MYBPC3 Mutation and Associated with Cardiac Dysfunction in Hypertrophic Cardiomyopathy(FRS19,Genetic Abnormalities in Cardiac Hypertrophy and Cardiomyopathy (M),Featured Research Sessi
- PJ-778 The Exact Location of the Branching point of the His Bundle(Arrhythmia, diagnosis / Pathophysiology / EPS(16)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-113 Nkx2.5(+) But Not Flk1(+) Cardiac Progenitor Cells are Fated to Pacemaker Cells Expressing I_f Predominantly Encoded by HCN4 Gene(Heart failure, basic(05)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation So
- PE-339 Losartan Improved Insulin Resistance and Decreased Inflammatory Cytokines in Patients with Chronic Heart Failure(Heart failure, clinical(10)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-332 Value of Routine Admission Laboratory test and Clinical Risk Factor to Predict in-hospital Mortality in Patients with Acute Myocardial Infarction(Emergency care/CPR(03)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese C
- PJ-513 Hyponatremia is an Important Predictor for In-hospital Mortality in Heart Failure Patients with Preserved Ejection Fraction(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulati
- PJ-513 Hyponatremia is an Important Predictor for In-hospital Mortality in Heart Failure Patients with Preserved Ejection Fraction(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulati
- Status of Uric Acid Management in Hypertensive Subjects
- PE-517 The Status of Hypertension Management in 2005 : Comparison with the Survey in 2000(Hypertension, clinical-08, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-458 Role of Cysteinyl Leukotrienes in the Proliferation and Migration of Mice Vascular Smooth Muscle cells in Vivo and in Vitro(Infection/Inflammation/Immunity-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Plasma Levels of Uridine Correlate With Blood Pressure and Indicators of Myogenic Purine Degradation and Insulin Resistance in Hypertensive Patients
- Allopurinol Reduces Neointimal Hyperplasia in the Carotid Artery Ligation Model in Spontaneously Hypertensive Rats
- Small Extra-Adrenal Pheochromocytoma Causing Severe Hypertension in an Elderly Patient
- PJ-082 Effect of an Angiotensin-receptor Antagonist and Low-dose Hydrochlorothiazide on Urate Metabolism in Hypertensive Patients Either with or without Hyperuricemia(Hypertension, clinical-11 (H) PJ14,Poster Session (Japanese),The 70th Anniversary Annual
- Extrinsic factors derived from mouse embryonal carcinoma cell lines maintain pluripotency of mouse embryonic stem cells through a novel signal pathway
- Neurohormonal Determinants of Peak Oxygen Uptake in Patients with Chronic Heart Failure
- FRS-002 Uricosuric Action of Losartan via the Inhibition of Urate Transporter 1 (URAT1) in Hypertensive Patients(New Clinical Aspects for Hypertension(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-520 Serum Uridine Levels Correlate with Blood Pressure and Indicators of Myogenic Purine Degradation, Anaerobic Glycolysis and Insulin Resistance in Hypertensives(Hypertension, clinical-08, The 71st Annual Scientific Meeting of the Japanese Circulation
- PJ-180 Subtype Swithing of T-type Ca^ Channels from Cav3.2 to Cav3.1 during Differentiation of Embryonic Stem Cells to Cardiac Cell Lineage(Excitation-contraction coupling/Ion channel-2 (A) PJ30,Poster Session (Japanese),The 70th Anniversary Annual Sc
- Subtype Switching of T-Type Ca^ Channels From Cav3.2 to Cav3.1 During Differentiation of Embryonic Stem Cells to Cardiac Cell Lineage
- Acute Myocardial Infarction in a Patient With Essential Thrombocythemia : Successful Treatment With Percutaneous Transluminal Coronary Recanalization
- Many of all Hypertensive Patients would Need Urine Alkalization in order to Prevent Progress of the Hypertension-merged Complications (Hypertension, Clinical 10 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OE-060 Clinical importance of myogenic hyperuricemia coupled with hypertension based on multiple risk factor clustering syndrome : roles of purine metabolites(Hypertension, Clinical 1 (H) : OE8)(Oral Presentation (English))
- Excess Release of Hypoxanthine from the Skeletal Muscles of Patients with Hypertension and Dyslipidemia Is Suppressed by HMG-CoA Reductase Inhibitors
- Genetic analysis of expression profile involved in retinoid metabolism in non-alcoholic fatty liver disease
- Remote Reperfusion Lung Injury is Associated With AMP Deaminase 3 Activation and Attenuated by Inosine Monophosphate
- OE-193 Exaggeration of Remote Reperfusion Pulmonary Injury in AMP Deaminase 3 Knockout Mice(Metabolism/Biochemistry/Energetics-1 (H) OE33,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Uric Acid Lowering Therapy Improves Endothelial Function in Patients with Hyperuricemia (Kidney/Renal Circulation 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-077 Molecular and structural basis for stabilization of short-lived ion channel proteins by Na^+ channel blockers(Arrhythmia, Basic 1 (A) : OJ10)(Oral Presentation (Japanese))
- A Novel Activity of Na^+ Channel Blockers to Inhibit Proteasomal Degradation of Kv1.5 Channels
- Proteasome inhibitors and Na channel blocker increase the KV1.5 channel activities by modification of the intracellular trafficking
- PJ-221 Differential Actions of Angiotensin II on Inward Rectifier K+ Currents in Atrial Myocytes Isolated from WKY Rats and SHRs(Hypertension, basic-3 (H) PJ37,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circul
- 4 Purine Metabolites as Bioenergetic Marker in the Patients with Cardiovascular Disease(Diagnosis of cardiovascular diseases with biochemical markers and the_new foresight,Roundtable Discussion 2 (RT2) (H),The 70th Anniversary Annual Scientific Meeting of
- A Novel Activity of a Na^+ Channel Blocker to Inhibit Proteasomal Degradation of Kir6.2 Channel and Increase Cardiac K_ Channels
- Coordinate Induction of AMP Catabolic Enzymes in Human Atrial Myocytes with Mitochondrial DNA Deletion : Novel Mechanism on Biochemical Atrial Remodeling
- Allopurinol Improves Cardiac Dysfunction After Ischemia-Reperfusion via Reduction of Oxidative Stress in Isolated Perfused Rat Hearts
- PJ-362 Antiinflammatory and Antiarteriosclerotic Effects of Fenofibrate in a Rat Model of Chronic Blockade of Nitric Oxide Synthesis(Molecular Biology, Vascular 2 (H) : PJ61)(Poster Session (Japanese))
- OJ-174 CYTOSOLIC PHOSPHOLIPASE-A2α GENE-DEFICIENT SUPPRESSED PROGRESSION of ATHEROSCLEROSIS in APOLIPOPROTEIN-E GENE DEFICIENT MICE(Infection/Inflammation/Immunity 1 (H) : OJ20)(Oral Presentation (Japanese))
- Excessive Purine Degradation during Semi-ischemic Forearm Test in Patients with Diabetes Mellitus
- Current Status of Lipid Management of Hypertensive Patients
- The Status of Hypertension Management in Japan in 2000
- Evaluation of Sympathetic Nerve Activity and Heart Rate Induced by Once-Daily Administration of Amlodipine and Nifedipine in Essential Hypertensive Patients
- Transient Left Ventricular Apical Ballooning in a Patient With Bicuspid Aortic Valve Created a Left Ventricular Thrombus Leading to Acute Renal Infarction
- No Smoking Prevents Acute Coronary Syndrome Most Cheaply and Efficiently
- Effect of the Angiotensin II Receptor Antagonist Losartan on Uric Acid and Oxypurine Metabolism in Healthy Subjects
- OE-152 The Electrophysiological and Anatomical Characteristics of the Myocardial Free Area Located in Right Atrium-Inferior Vena Cava Junction(Arrhythmia, diagnosis/pathophysiology/EPS-02, The 71st Annual Scientific Meeting of the Japanese Circulation Soc
- PJ-450 Atrial Coronary Arteries in Left Atrium : Clinical Implication Related to Radiofrequency Liner Catheter Ablation for Atrial Fibrillation(Arrhythmia, diagnosis/pathophysiology/EPS-11 (A) PJ76,Poster Session (Japanese),The 70th Anniversary Annual Sci
- PE-136 The Influence of the sub-Eustachian Pouch on the Cavotricuspid Isthmus Ablation(Arrhythmia, diagnosis/pathophysiology/EPS-8 (A) PE23,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-397 Anatomical Characteristics of Mitral Isthmus in Japanese(Arrhythmia, diagnosis/pathophysiology/EPS-5 (A) OJ67,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-351 Soluble Cytokine Receptors and Soluble Fas in Relation to Cardiopulmonary Exercise Variables in Patients with Chronic Heart Failure(Exercise Test/Cardiac Rehabilitation 4 (IHD) : OJ42)(Oral Presentation (Japanese))
- Edaravone Applied at Reoxygenation Reduces the Hypoxia-Induced Cell Death in Rabbit Cardiomyocytes
- PJ-495 Intracellular AMP Inhibits PKA to Attenuate β-Adrenergic Signaling : Evidence from Isolated Cardiac Cells and AMP Deaminase 3 Knock-Out Mice(Arrhythmia, Basic 5 (A) : PJ83)(Poster Session (Japanese))
- OJ-017 Developmental stage-dependent contribution of T-type Ca^ current and I_f to automaticity in ES-derived cardiac myocytes(Excitation-Contraction Coupling/Ion Channel (A) : OJ3)(Oral Presentation (Japanese))
- Addition of Losartan to Angiotensin-Converting Enzyme Inhibitors Improves Insulin Resistance in Patients With Chronic Heart Failure Treated Without β-Blockers
- Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin
- Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy
- Factors Contributing to Hyperuricemia in Patients with Congestive Heart Failure(Heart Failure, Clinical 6 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- New Electrocardiographic Criteria to Distinguish between Slow/Slow Atrioventricular Nodal Reentrant Tachycardia and Atrioventricular Reentrant Tachycardia Using Postroseptal Accessory Pathway(Arrhythmia, Diagnosis/Pathophysiology/EPS 11 (A), The 69th Annu
- Long-term Observation of the Patinets with Sinus Node Dysfunction Treated with Single Chamber Atrial Pacing(Arrhythmia, Non-pharmacological Therapy 2 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Neurohumoral Profiles in Patients With Hypertrophic Cardiomyopathy : Differences to Hypertensive Left Ventricular Hypertrophy
- Effects of Angiotensin II Type 1 Receptor Antagonist, Losartan, on Ventilatory Response to Exercise and Neurohormonal Profiles in Patients with Chronic Heart Failure
- Activation of anaerobic glycolysis diminishes adenosine production but increases the substrate for xanthine oxidase of skeletal muscles in hypertensive patients
- PJ-307 Hyperuricemia in congestive heart failure : A new therapeutic target of heart failure(Heart Failure, Clinical 6 (M) : PJ52)(Poster Session (Japanese))
- Cytokine Abnormalities and Soluble Fas in Relation to Neurohormonal Activation and Exercise Capacity in Patients with Chronic Heart Failure
- Purine Degradation and Sympathetic Activation at Maximal Exercise in Subjects with Varying Degrees of Exercise Tolerance
- Neurohormonal Determinants of Peak Oxygen Uptake in Patients with Mild to Moderate Chronic Heart Failure
- Atrial natriuretic peptide and norepinephrine levels predict VE/VCO2 slope during exercisein patients with chronic heart failure
- The morphological features of fossa ovalis in Man : Eletrophysiological role as an anatomical obstacle
- PJ-168 Predictors of the Recurrence of Atrial Fibrillation after Cavotricuspid Isthmus Ablation in Patients with Common Atrial Flutter(Arrhythmia, Non-Pharmacological Therapy 6 (A) : PJ28)(Poster Session (Japanese))
- PJ-165 Hypertension is A Predictor of Recurrence of Atrial Fibrillation in Patients with Sinus Node Dysfunction Treated with Atrial Pacing(Arrhythmia, Non-Pharmacological Therapy 6 (A) : PJ28)(Poster Session (Japanese))
- PJ-015 Electrophysiological Effects of Angiotensin II on Atrial Tissue(Arrhythmia, Diagnosis/Pathophysiology/EPS 5 (A) : PJ3)(Poster Session (Japanese))
- PJ-012 The role of crista terminalis in common atrial flutter, critical pathway or blocking site?(Arrhythmia, Diagnosis/Pathophysiology/EPS 4 (A): PJ2)(Poster Session (Japanese))
- A Variety of the Isthmus Anatomy in Patients with Atrial Flutter : The Relationship with the History of Hypertension
- The Dimension of Coronary Sinus Musculature