Plasma Catecholamine Levels in the Coronary Sinus, Aorta and Femoral Vein of Subjects Undergoing Cardiac Catheterization at Rest and During Exercise.
スポンサーリンク
概要
- 論文の詳細を見る
Plasma catecholamine (CA) levels in the coronary sinus (CS), aorta (Ao) and femoral vein (FV) were simultaneously measured in 22 patients with various heart diseases at rest and during handgrip exercise (IHG). The mean resting levels of plasma norepinephrine (NE) in CS, Ao and FV were 359±49 (SEM) pg/ml, 290±27 and 234±24, respectively. The corresponding values of epinephrine (E) were 127±18 pg/ml, 186±30 and 97±11, respectively. The E values in Ao were significantly greater than those in CS and in FV (p<0.05). IHG exercise induced an obvious elevation of plasma CA levels in every portion of the circulation studied. The mean increments of NE concentration were 81%, 54% and 67% of the resting levels at CS, Ao and FV respectively, while IHG induced elevation of E were 70% of the resting values at each portion studied. Significant correlations were observed between individual CA concentrations in CS and in Ao, and also between those in Ao and in FV at rest. Under raised sympathoadrenal conditions, however, individual values of NE in CS failed to correlate significantly to those in Ao and in FV, respectively. The NE output from CS was limited to only 3% and 5% of those in Ao at rest and during IHG, respectively. An actual mean increment of NE on its passing through the coronary circulation was only 2% or less of NE output in Ao at both stages. It appears, thus, to be untenable that the cardiac tissue is one of the major source of circulating CA at physiological condition. From these reasons, the direct measurement of NE levels in CS may be mandatory, when plasma CA assay is designed for the purpose of studying the role of the sympathetic nerve activity in the regulation of cardiac function.
- 社団法人日本循環器学会の論文
- 1976-09-20
著者
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SHIRATO Kunio
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
-
Yoshinaga Kaoru
The Second Department Of Internal Medicine Tohoku University School Of Medicine
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YOSHINAGA KAORU
Department of Internal Medicine, Tohoku University School of Medicine
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Haneda Takashi
The First Dept. Of Int. Med. Tohoku Univ. School Of Med.
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Haneda Takashi
The First Department Of Internal Medicine
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Shirato Kunio
Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine
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MIURA Yukio
Department of Informatics on Pathophysiology, Tohoku University Graduate School of Information Scien
-
Miura Yukio
The Department Of Informatics On Pathophysiology Tohoku University Graduate School Of Information Sc
-
Miura Yukio
The Second Department Of Internal Medicine Tohoku University School Of Medicine
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Sato T
Fourth Department Of Internal Medicine Fukuoka University School Of Medicine
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Miyazawa Kozui
The 1st Dept. Of Intern. Med. Tohoku Univ. School Of Med.
-
Miyazawa Kozui
Department Of Laboratory Medicine Yamagata University School Of Medicine
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Miyazawa Kozui
Department Of Biochemistry Yamagata University School Of Medicine
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Haneda Takashi
1st Dept Of Intern. Med. Tohnku
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Sato Tatsuo
The Ist And The 2nd Dept. Of Intern. Med. Tohoku Univ. School Of Med
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Miyazawa Kozui
The 1st And 2nd Dept.of Intern.med.tohoku Univ.school Of Med.
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Miura Yukio
Department Of Internal Medicine Tohoku University School Of Medicine
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SATO TATSUO
Department of Internal Medicine, Tohoku University School of Medicine
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MINAI KOJI
Department of Internal Medicine, Tohoku University School of Medicine
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KOBAYASHI KIYOSHI
Department of Internal Medicine, Tohoku University School of Medicine
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Sakuma Hisaichi
The 2nd Department Of Internal Medicine Tohoku University School Of Med
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HANEDA Takashi
Department of Internal Medicine, Asahikawa Medical College
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Yoshinaga Kaoru
Dept. Of Intern. Med. Tohoku Univ. Shool Of Medicine
-
Yoshinaga Kaoru
Department Of Internal Medicine Tohoku University School Of Medicine
-
Kobayashi Kiyoshi
The 2nd Department Of Internal Medicine Tohoku University School Of Med
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Minai Koji
Department Of Lnternal Medicine Tohoku University School Of Medicine
-
Miura Yukio
The 2nd Department Of Internal Medicine Tohoku University School Of Med
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SAKUMA HISAICHI
Department of lnternal Medicine, Tohoku University School of Medicine
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HONNA TAKAO
Department of lnternal Medicine, Tohoku University School of Medicine
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TAKISHIMA TAMOTSU
Department of lnternal Medicine, Tohoku University School of Medicine
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Miura Y
The Department Of Informatics On Pathophysiology Tohoku University Graduate School Of Information Sc
-
Yoshida Kazunori
Department Of Internal Medicine And Rehabilitation Science Tohoku University Graduate School Of Medi
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Sato Tatsuo
Department Of Internal Hokkaido University School Of Medicine
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Yoshinaga Kaoru.
The 2nd Department Of Internal Medicine Tohoku University School Of Med
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Kobayashi Kiyoshi
Department Of Clinical Physiology Akita City General Hospital
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HANEDA Takashi
Department of Cardiology, Cedars-Sinai Medical Center and the Department of Medicine, UCLA School of Medicine
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SATO TATSUO
Department of Chemical Engineering, Nagoya University
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