Monophasic Action Potential Duration at the Crista Terminalis in Patients With Sinus Node Disease
スポンサーリンク
概要
- 論文の詳細を見る
Background The repolarization properties of the crista terminalis (CT) cells have not been elucidated in patients with sinus node disease (SND). In the present study a new technique of recording the monophasic action potential (MAP) at the CT was used to examine the repolarization of the right atrium (RA) in SND patients. Methods and Results Symptomatic SND (n=13) patients and age-, sex-matched control patients (n=13) were tested. The MAP duration (MAPD) at a basic cycle length of 600ms was recorded at the CT in the superior vena cava-RA junction and at the middle-anterior RA with the effective refractory period (ERP) at the high RA. In 6 controls and 4 SND patients, the effect of adenosine triphosphate on the MAPD was examined. The MAPD at the CT exceeded that at the middle-anterior RA in both groups. The MAPD at the CT in the SND group was significantly prolonged compared with the control group (CT : 358±39ms vs 289±43ms). Between the SND and control groups, the MAPD at the middle-anterior RA (278±36ms vs 265±39ms) and ERP (294±42ms vs 266±41ms) did not differ. Both the corrected-sinus node recovery time and sinoatrial conduction time were better correlated with the MAPD at the CT than the MAPD at the middle-anterior RA and ERP. Adenosine triphosphate shortened the MAPD, which was augmented at the CT in the SND patients. Conclusion A novel method of estimating the MAP at the CT revealed the characteristics of atrial repolarization in SND patients.
- 社団法人日本循環器学会の論文
- 2005-10-20
著者
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KAGAYA Yutaka
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
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Kagaya Yutaka
Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine
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Kagaya Yutaka
東北大学 医学系研究科循環器病態学
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WATANABE Jun
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
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SHINOZAKI Tsuyoshi
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
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SHIRATO Kunio
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
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Takahashi Chiaki
東北大学 医学部量子診断学
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Shirato Kunio
山口大学 医学系研究科器官病態内科学
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Watanabe Jun
Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine
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Katoh Hiroshi
Department of Cardiovascular Medicine, Tohoku Rosai Hospital
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Baba Shigeo
Department of Cardiovascular Medicine, Graduate School of Medicine Tohoku University
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Satoh Shoichi
Department of Internal Medicine, Kamaishi City Hospital
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Shirato Kunio
Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine
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Baba Shigeo
Department Of Cardiovascular Medicine Graduate School Of Medicine Tohoku University
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Satoh S
Department Of Internal Medicine Kamaishi City Hospital
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Satoh Syoichi
The First Department Of Internal Medicine Tohoku University
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Satoh Shoichi
X Ray Research Laboratory Rigaku Corporation
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Shinozaki Tsuyoshi
Department Of Cardiovascular Medicine Sendai Medical Center
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Kanai Hiroshi
Education Center For Information Processing Tohoku University
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Satoh Syoichi
The 1st Dept. Of Internal Medicine Tohoku University School Of Medicine
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Satoh Shoichi
Department Of Internal Medicine Kamaishi City Hospital
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Kan-no Yuka
The 1st Department Of Internal Medicine Tohoku University School Of Medicine
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Sato Sotaro
The First Dep. Of Int. Med. Tohoku Univ. School Of Medicine Sendai
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Suzuki Takashi
Department Of Radiology Tohoku University Graduate School Of Medicine
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Watanabe J
Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine
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Watanabe Jun
Department Of Anatomy & Cell Science Kansai Medical University
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Katoh Hiroshi
Department Of Cardiology Katta General Hospital
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KATOH Hiroshi
Department of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu University
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