EFFECTS OF LONG-TERM β-BLOCKADE (METOPROLOL) THERAPY IN PATIENTS WITH DILATED CARDIOMYOPATHY
スポンサーリンク
概要
- 論文の詳細を見る
Twenty-two patients with dilated cardiomyopathy (DCM) were treated with metoprolol and their clinical courses were compared with those of 26 patients untreated with β-blocking agents (non β group). Of the 22 patients treated with metoprolol, 19 ( β group) were treated for a long period. 3 patients left the study within its first 6 months. Using the NYHA classification, 4 patients of the β group were evaluated as having clinically improved. while none was aggravated. excluding 2 cases of death which occurred during the follow up period. In the non-β group. clinical improvement was found for 2 patients and aggravation in functional class for 10. The left ventricular diameter was significantly decreased and parameters of systolic function and exercise tolerance were significantly improved in patients of the β group. while no such improvements occurred in patients of the non-β group. Twenty-four-hour ECG monitoring demonstrated a significant reduction in incidences of ventricular extrasystole in the β group but not in those of the non-β group. Improvement of arrhythmias, evaluated using Lown's grading system, was also identified more frequently in the β group than in the non-p group. During the follow-up period. 2 patients of the β group and 10 patients of the non-β group died. The survival curve for patients of the β group prepared using the Caplan Meier Method was better than that for patients of the non-β group. Metoprolol was therefore found to be useful for treatment of DCM.
- 社団法人日本循環器学会の論文
- 1991-04-20
著者
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Fukuzaki H
Miki City Hospital Department Of Cardiology
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Yokota Yoshiyuki
Division Of Cardiovascular And Respiratory Medicine Kobe University Graduate School Of Medicine
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Yasaka Yoshinori
Division Of Cardiovascular And Respiratory Medicine Kobe University Graduate School Of Medicine
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KUROZUMI Hiroaki
The 1st Department of Internal Medicine. Kobe University School of Medicine
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Yokota Yoshiyuki
The First Department of Internal Medicine, Kobe University School of Medicine
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Takarada Akira
The First Department of Internal Medicine, Kobe University School of Medicine
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Fukuzaki Hisashi
The First Department Of Internal Medicine Kobe University School Of Medicine
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Yasaka Yoshinori
Department Of Cardiology Himeji Cardiovascular Center
-
Nomura Hideki
The First Department Of Internal Medicine Kobe University School Of Medicine
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Takarada Akira
Department Of Cardiology Himeji Cardiovascular Center
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Yoshida Y
Faculity Of Health Science Kobe University School Of Medicine
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Takeuchi Yoshio
The First Department of Medicine, Kobe University School of Medicine
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Takeuchi Yoshio
The 1st Department of Internal Medicine, Kobe University School of Medicine
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Fukuzaki Hisashi
Department Of Thoracie Srugery Osaka Medical College
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Fukuzaki Hisashi
Dept Of Intern Med. Div. I Kobe Univ. School Of Med.
-
Yoshida Yutaka
Dept. Of Intern.med Kobe Univ. School Of Med.
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TSUMURA YASUHIRO
The First Department of Internal Medicine, Kobe University School of Medicine
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KAWAI HIROYA
The First Department of Internal Medicine, Kobe University School of Medicine
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KUROZUMI HIROAKI
The First Department of Internal Medicine, Kobe University School of Medicine
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Kawai Hiroya
Division Of Cardiovascular And Respiratory Medicine Department Of Internal Medicine Kobe University
-
Kawai Hiroya
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
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Kawai Hiroya
The First Department Of Internal Medicine Kobe University School Of Medicine
-
Kurogane Hiroyuki
The First Department Of Internal Medicine School Of Medicine Kobe University
-
Kawai Hiroya
Himeji Cardiovascular Center
-
Fukuzaki Hisasi
Dept. of Intern. Med. Kobe Univ. school of Med.
-
Kurogane Hiroyuki
Department Of Cardiology Miki City Hospital
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Kawai Hiroya
Division Of Cardiovascular And Respiratory Medicine Kobe University Graduate School Of Medicine
-
Fukuzaki Hisashi
The First Department Of Internal Medicine Kobe University
-
Yoshida Yutaka
The First Department Of Internal Medicine Kobe University School Of Medicine
-
Yokota Yoshiyuki
The First Department Of Internal Medicine
-
Tsumura Yasuhiro
The First Department Of Internal Medicine Kobe University School Of Medicine
-
Fukuzaki Hisashi
Dept. Of Int. Med. Div1 Kobe Univ.
-
Kawanishi Hideo
The First Department Of Internal Medicine Kobe University School Of Medicine
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Kawai Hiroya
Kobe University Graduate School Of Medicine Division Of Cardiovascular Medicine Department Of Intern
-
Kawai Hiroya
The Ist Department Of Internal Medicine Kobe University School Of Medicine
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Yoshida Y
1gunma Univ.
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Fukuzakl Hisashi
The First Department Of Internal Medicine Kobe University School Of Medicine
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Fukuzaki Hisashi
1st Dep. Of Internal Med. Kobe Univ.
-
Fukuzaki Hisashi
Department Of Thoracic Surgery Osaka Medical College
-
Fukuzaki Hisashi
Internal Medicine Division I Kobe University
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Yoshida Yutaka
Hyogo Brain and Heart Center at Himeji
-
Fukuzaki Hisashi
The 1st.dept.of Inter. Med Kobe Univ. School Of Med.
-
Takarada Akira
First Division Department Of Internal Medicine Kobe University School Of Medicine
-
Kawai Hiroya
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
-
Yoshida Yutaka
Dept. Of Intern. Med. Div. I Kobe Univ. School Of Med.
-
Kawai Hiroya
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
-
Kurozumi Hiroaki
The 1st Department Of Internal Medicine Kobe University Shool Of Medicine
-
Kawai Hiroya
The 1st Department Of Internal Medicine Kobe University School Of Medicine
-
Kurozumi Hiroaki
The First Department Of Internal Medicine Kobe University School Of Medicine
-
Fukumoto Hitoshi
Department Of Thoracie Srugery Osaka Medical College
-
Kawai Hiroya
Division Of Cardiovascular Medicine Department Of Internal Medicine Kobe University Graduate School
-
Takarada Akira
The First Department Of Internal Medicine Kobe University School Of Medicine
-
Fukuzaki Hisashi
First Department Of Internal Medicine. Kobe University School Of Medicine
-
Yasaka Yosninori
The 1st Department Of Internal Medicine Kobe University School Of Medicine
-
Takeuchi Yoshio
The First Department Of Internal Medicine Kobe University School Of Medicine
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