Perfusable tissue index obtained by positron emission tomography as a marker of myocardial viability in patients with ischemic ventricular dysfunction
スポンサーリンク
概要
- 論文の詳細を見る
In areas of severe asynergy, the clinically important task is to identify functionally recoverable myocardium. Fourteen patients with asynergy were investigated by H215O dynamic positron emission tomography imaging before revascularization. Regional myocardial blood flow (MBF) was determined and the water-perfusable tissue fraction (PTF) for each region of interest and the total anatomical tissue fraction (ATF) were estimated. The PTF/ATF was analyzed as the water perfusable tissue index (PTI). Asynergy was defined as segments with wall motion more than 2 SD below than that of a normal population. An increase of >0.8 SD in anterior wall segments with asynergy and an increase of >0.6 SD in inferior wall asynergy were defined as significant improvements of wall motion indicative of viable myocardium. Fifteen segments with wall motion abnormalities less than -2 SD and 10 control segments were identified; 7 segments recovered and 8 segments did not. MBF was similar in both groups of segments before revascularization (0.78±0.27 vs 0.73±0.18 ml · min-1 · g-1, NS). The PTI in the recovered segments was significantly higher than that in the unimproved segments (0.734±0.058 vs 0.592±0.038, p<0.0001) and was similar to that of the control segments. After revascularization, the PTI correlated with the SD of wall motion (p<0.05, r=0.58). PTI may be a good predictor of contractile recovery after revascularization.
- 社団法人日本循環器学会の論文
- 2002-03-20
著者
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FUJII Hiroyuki
Department of Cardiology, Yokohama-Minami Kyosai Hospital
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Shimizu Masami
the Second Department of Internal Medicine, Kanazawa University Hospital
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Itoh Hideki
Department Of Cardiovascular And Respiratory Medicine Shiga University Of Medical Science
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Namura Masanobu
Department of Cardiology, Kanazawa Cardiovascular Hospital
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Uenishi Hiroaki
Department of Cardiology, Kanazawa Medical University
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MABUCHI Hiroshi
The Second Department of Internal Medicine, School of Medicine, Kanazawa University
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Tsuchiya Taketsugu
Deparment Of Cardiology Kanazawa Cardiovascular Hospital
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Tsuchiya Taketsugu
Departments Of Cardiology Kanazawa Cardiovascular Hospital
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Fujii Hiroyuki
Department Of Cardiology Yokohama-minami Kyosai Hospital
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Asai Toru
Department Of Cardiology Aichi Cardiovascular And Respiratory Center
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Asai Toru
Departments Of Thoracic And Cardiovascular Surgery Kanazawa Cardiovascular Hospital
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Fujii Hiroyuki
Komatsu Municipal Hospital
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ITO Jun
Department of Radiology, Maebashi Red Cross Hospital
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Namura Masanobu
Deparment Of Cardiology Kanazawa Cardiovascular Hospital
-
Namura Masanobu
2nd Department Of Internal Medicine Kanazawa University School Of Medicine
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Fujita Hiromi
Ohara General Hospital Fukushima Jpn
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Seki Hiroyuki
Departments of Radiology, Kanazawa Cardiovascular Hospital
-
Fujita Shinichirou
Departments of Cardiology, Kanazawa Cardiovascular Hospital
-
Tanabe Yujirou
Departments of Cardiology, Kanazawa Cardiovascular Hospital
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Mabuchi Hiroshi
The Second Department Of Internal Medicine
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Shimizu Masami
The Second Department Of Internal Medicine School Of Medicine Kanazawa University
-
Tanabe Yujirou
Departments Of Cardiology Kanazawa Cardiovascular Hospital
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Uenishi Hiroaki
Department Of Cardiology Kanazawa Medical University
-
Uenishi Hiroaki
Departments Of Cardiology Kanazawa Cardiovascular Hospital
-
Itoh Hideki
Department Of Emergency And Critical Care Medicine Kanazawa University Hospital
-
Fujita Shinichirou
Departments Of Cardiology Kanazawa Cardiovascular Hospital
-
Seki Hiroyuki
Department Of Applied Chemistry Graduate School Of Engineering Kanagawa University
-
Shimizu Masami
The Second Department Of Internal Medicine Kanazawa University Hospital
-
Itoh Hideki
Department Of Anesthesiology And Critical Care Medicine Yokohama City University Graduate School Of
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Seki Hiroyuki
Departments Of Radiology Kanazawa Cardiovascular Hospital
-
Ito Jun
Departments Of Cardiology Kanazawa Cardiovascular Hospital
-
Ito Jun
Department Of Anesthesiology Tohoku University Postgraduate Mdical School
-
Namura Masanobu
Department Of Cardiology Kanazawa Cardiovascular Hospital
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Fujita Shinichiro
Departments of Cardiology, Kanazawa Cardiovascular Hospital
-
Tanabe Yujirou
Department of Cardiology, Kanazawa Medical University
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